Algorithmic Complexity of EEG for Prognosis of Neurodegeneration in Idiopathic Rapid Eye Movement Behavior Disorder (RBD)

Annals of Biomedical Engineering
Giulio RuffiniAureli Soria-Frisch

Abstract

Idiopathic rapid eye movement sleep behavior disorder (RBD) is a serious risk factor for neurodegenerative processes such as Parkinson's disease (PD). We investigate the use of EEG algorithmic complexity derived metrics for its prognosis. We analyzed resting state EEG data collected from 114 idiopathic RBD patients and 83 healthy controls in a longitudinal study forming a cohort in which several RBD patients developed PD or dementia with Lewy bodies. Multichannel data from ~ 3 min recordings was converted to spectrograms and their algorithmic complexity estimated using Lempel-Ziv-Welch compression. Complexity measures and entropy rate displayed statistically significant differences between groups. Results are compared to those using the ratio of slow to fast frequency power, which they are seen to complement by displaying increased sensitivity even when using a few EEG channels. Poor prognosis in RBD appears to be associated with decreased complexity of EEG spectrograms stemming in part from frequency power imbalances and cross-frequency amplitude algorithmic coupling. Algorithmic complexity metrics provide a robust, powerful and complementary way to quantify the dynamics of EEG signals in RBD with links to emerging theories of...Continue Reading

References

Jul 15, 1987·Physical Review A: General Physics·F Kaspar, H G Schuster
Jan 5, 2002·IEEE Transactions on Bio-medical Engineering·X S ZhangE W Jensen
Jun 5, 2003·Annals of Neurology·Maria Livia FantiniJacques Montplaisir
Oct 5, 2011·Annals of Biomedical Engineering·Carlos GómezRoberto Hornero
Aug 16, 2013·Science Translational Medicine·Adenauer G CasaliMarcello Massimini
Nov 8, 2015·Neurobiology of Aging·Jessica Rodrigues BrazèteJacques Montplaisir
Dec 29, 2015·Brain Connectivity·Josie-Anne BertrandJean-François Gagnon
Feb 26, 2016·Brain : a Journal of Neurology·Véronique LatreilleJean-François Gagnon
May 27, 2016·Nature Reviews. Neuroscience·Giulio TononiChristof Koch
Jun 14, 2016·Neuroscience Letters·Anthony G HudetzGiulio Tononi
Jun 17, 2016·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Thomas AndrillonSid Kouider
Apr 20, 2017·Scientific Reports·Michael M SchartnerSuresh D Muthukumaraswamy
Nov 6, 2017·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Yoon KimBeomseok Jeon
Nov 25, 2017·Nature Reviews. Neurology·Birgit HöglAleksandar Videnovic

❮ Previous
Next ❯

Citations

Mar 9, 2019·Biomedizinische Technik. Biomedical Engineering·Caglar UyulanNevzat Tarhan
Feb 6, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Cathy A GoldsteinAnita V Shelgikar
Oct 3, 2020·Annals of Biomedical Engineering·Abdul Haleem ButtFilippo Cavallo
Aug 17, 2019·Frontiers in Neurology·Giulio RuffiniJacques Montplaisir
Jul 16, 2019·Movement Disorders : Official Journal of the Movement Disorder Society·Marco OnofrjStefano L Sensi
May 6, 2020·Experimental Brain Research·Marta CastellanoGiulio Ruffini
Jul 7, 2019·Expert Review of Neurotherapeutics·Luigi Ferini-StrambiAndrea Galbiati

❮ Previous
Next ❯

Software Mentioned

LZW

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.