ALIF and total disc replacement versus 2-level circumferential fusion with TLIF: a prospective, randomized, clinical and radiological trial

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Eike HoffMichael Putzier

Abstract

Prospective, randomized trial. The treatment of degenerative disc disease (DDD) with two-level fusion has been associated with a reasonable rate of complications. The aim of the present study was to compare (Hybrid) stand-alone anterior lumbar interbody fusion (ALIF) at L5/S1 with total disc replacement at L4/5 (TDR) as an alternative surgical strategy to (Fusion) 2-level circumferential fusion employing transforaminal lumbar interbody fusion (TLIF) with transpedicular stabilization at L4-S1. A total of 62 patients with symptomatic DDD of segments L5/S1 (Modic ≥2°) and L4/5 (Modic ≤2°; positive discography) were enrolled; 31 were treated with Hybrid and 31 with Fusion. Preoperatively, at 0, 12, and a mean follow-up of 37 months, clinical (ODI, VAS) and radiological evaluations (plain/extension-flexion radiographs evaluated for implant failure, fusion, global and segmental lordosis, and ROM) were performed. In 26 of 31 Hybrid and 24 of 31 Fusion patients available at the final follow-up, we found a significant clinical improvement compared to preoperatively. Hybrid patients had significantly lower VAS scores immediately postoperatively and at follow-up compared to Fusion patients. The complication rates were low and similar betw...Continue Reading

References

Sep 21, 2001·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·M N KumarH Hall
Sep 21, 2001·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·M N KumarD Chopin
Mar 3, 2005·The Journal of Bone and Joint Surgery. American Volume·Patrick TropianoThierry Marnay
Sep 9, 2006·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·C TournierW Skalli
Jan 11, 2007·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Cédric BarreyPierre Roussouly
Apr 7, 2007·Spine·Christoph J SiepeAndreas Korge
Sep 23, 2008·The Spine Journal : Official Journal of the North American Spine Society·Steven D GlassmanMitchell J Campbell
Aug 1, 2009·Spine·Frank SchwabJean-Pierre Farcy
Oct 31, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·ShunWu FanXiangqian Fang
Nov 6, 2009·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Stephane AunobleJean-Charles Le Huec
Jan 16, 2010·Journal of Spinal Disorders & Techniques·Hooshang SaberiLeila Jahani
Aug 5, 2010·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Patrick StrubeMichael Putzier
Aug 2, 2011·Joint, Bone, Spine : Revue Du Rhumatisme·Jean Charles Le Huec
Aug 17, 2011·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·N PelletJ C Le Huec
May 4, 2012·The Journal of the American Academy of Orthopaedic Surgeons·Jesse Chrastil, Alpesh A Patel
May 25, 2012·Archives of Orthopaedic and Trauma Surgery·Sheng-Dan JiangLei-Sheng Jiang
Dec 12, 2012·Clinical Spine Surgery : a Spine Publication·Patrick StrubeMichael Putzier
Apr 23, 2013·Journal of Neurosurgery. Spine·Sean M Jones-QuaidooLeah Y Carreon
Jul 24, 2013·The Spine Journal : Official Journal of the North American Spine Society·Ozgur DedeVedat Deviren
Aug 27, 2013·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Patrick StrubeMichael Putzier
Jan 28, 2014·Clinical Orthopaedics and Related Research·Christina L GoldsteinY Raja Rampersaud
Oct 5, 2014·The Spine Journal : Official Journal of the North American Spine Society·Hiroyuki Yoshihara, Daisuke Yoneoka

❮ Previous
Next ❯

Citations

Dec 30, 2015·Journal of Korean Neurosurgical Society·Chun Kun Park
Apr 29, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Michael Putzier, Patrick Strube
Apr 23, 2015·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Jianqiang NiGuoan Li
Aug 26, 2016·Asian Spine Journal·Yu Chao LeeOrso Lorenzo Osti
Jul 28, 2016·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Fan DingMing Liu
Nov 15, 2019·Neurosurgery·Faheem A SandhuRolando Garica
Mar 27, 2021·Journal of Occupational and Environmental Medicine·Kurt T HegmannJeffrey S Harris
Oct 13, 2020·Clinical Spine Surgery : a Spine Publication·Hyun-Jae ChoChun Kee Chung

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.