PMID: 45256Dec 1, 1979

Alkaline phosphatase activity of the bursa of Fabricius: histochemical study in the normal embryo and during allograft reactions

Bulletin de l'Association des anatomistes
H Gérard


Alkaline phosphatase activity allows a certain discrimination between lympho-inhibition following a direct action on the lymphoid stem cells or a modification of mesenchyme/epithelium interactions; in this study we have compared the evolution of this activity in untreated chick embryos and in chick embryos following graft-versus-host-reactions. The important decrease of mesenchyme alkaline phosphatase activity induced here, involves a localisation of allograft reaction in this tissue; this result does not agree with the former explanations about a direct action on the lymphoid stem cells.

Related Concepts

Establishment and Maintenance of Localization
Bursa of Fabricius
Entire Embryo
Graft Vs Host Reaction
Alkaline Phosphatase
Alkaline Phosphatase Activity
Chick Embryo

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.