Alkaline phosphatase in stem cells

Stem Cells International
Kateřina ŠtefkováJiří Pacherník

Abstract

Alkaline phosphatase is an enzyme commonly expressed in almost all living organisms. In humans and other mammals, determinations of the expression and activity of alkaline phosphatase have frequently been used for cell determination in developmental studies and/or within clinical trials. Alkaline phosphatase also seems to be one of the key markers in the identification of pluripotent embryonic stem as well as related cells. However, alkaline phosphatases exist in some isoenzymes and isoforms, which have tissue specific expressions and functions. Here, the role of alkaline phosphatase as a stem cell marker is discussed in detail. First, we briefly summarize contemporary knowledge of mammalian alkaline phosphatases in general. Second, we focus on the known facts of its role in and potential significance for the identification of stem cells.

References

Jul 1, 1978·Annals of Human Genetics·R A MulivorH Harris
Jun 1, 1990·Cell Differentiation and Development : the Official Journal of the International Society of Developmental Biologists·C L MummeryS Shen
Jan 1, 1990·Virchows Archiv. A, Pathological Anatomy and Histopathology·J HustinP Franchimont
Mar 20, 1991·Journal of Molecular Biology·E E Kim, H W Wyckoff
Sep 1, 1989·Biology of Reproduction·M L Lepire, C A Ziomek
Jul 7, 1987·Biochimica Et Biophysica Acta·R A StinsonH B Collier
Oct 1, 1967·The Biochemical Journal·R P CoxM J Griffin
Aug 1, 1970·Clinica Chimica Acta; International Journal of Clinical Chemistry·W Fishman, H G Sie
Sep 1, 1967·Archives of Biochemistry and Biophysics·J G Georgatsos
Nov 1, 1994·Developmental Dynamics : an Official Publication of the American Association of Anatomists·S NarisawaJ L Millán
Jan 1, 1994·The Journal of Clinical Investigation·A MahmoodD H Alpers
May 1, 1997·Experimental Cell Research·M Buehr
Dec 11, 1999·Cells, Tissues, Organs·J RohwedelA M Wobus
Sep 7, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M KovaríkováA Kozubík
Sep 13, 2001·Molecular Reproduction and Development·N ShimadaT Matsuzawa
Apr 9, 2002·The Journal of Biological Chemistry·Alexey KozlenkovJosé Luis Millán
Oct 10, 2002·The Journal of Biological Chemistry·Marie-Hélène Le Du, Jose Luis Millan
Dec 3, 2002·The American Journal of Surgical Pathology·Jeffrey D GoldsmithPaul J Zhang
Jan 4, 2003·Reproduction, Nutrition, Development·Jirí PacherníkAles Hampl
Oct 16, 2003·Molecular and Cellular Biology·Sonoko NarisawaJosé Luis Millán
Apr 28, 2004·Developmental Biology·Irene GinisMahendra S Rao
Jun 2, 2004·Cellular and Molecular Life Sciences : CMLS·V BryjaA Hampl
Aug 26, 2004·The Journal of Biological Chemistry·Nicholas R D PalingMelanie J Welham
Dec 15, 2004·Anatomy and Embryology·Folker E FrankeKlaus Steger
Dec 30, 2004·Development·Thomas P Zwaka, James A Thomson
Jan 22, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Jeong M KimBarry P Sleckman
Mar 12, 2005·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Thomas M Ulbright
Apr 30, 2005·The Journal of Biological Chemistry·David J RoddaPaul Robson

❮ Previous
Next ❯

Citations

Apr 12, 2016·Chinese Medical Journal·Feng-Jiao LiQiu-Ju Wang
Dec 8, 2016·Reproduction in Domestic Animals = Zuchthygiene·G B de SouzaJrv Silva
Mar 24, 2016·Balsaeng'gwa saengsig·Yun-Gwi ParkSe-Pill Park
Feb 28, 2018·Molecular and Cellular Biology·Maria PliatskaDimitris Thanos
Sep 2, 2017·The Journal of Experimental Biology·Patricia CavelierClaude Delsert
May 31, 2019·Journal of Tissue Engineering and Regenerative Medicine·Sophia FernandesLalita Limaye
Dec 31, 2015·In Vitro Cellular & Developmental Biology. Animal·Sophia R BlochNiels C Bols
Aug 30, 2019·Arteriosclerosis, Thrombosis, and Vascular Biology·Emma J AkersBelinda A Di Bartolo
Mar 4, 2020·Zygote : the Biology of Gametes and Early Embryos·Tania Janeth Porras-Gómez, Norma Moreno-Mendoza
Jun 27, 2020·Regenerative Medicine·Francis KaranuLisa Stehno-Bittel
Jun 23, 2020·Antioxidants & Redox Signaling·Sebastiano GiallongoManlio Vinciguerra
Oct 4, 2019·Nature Communications·Elisa PedoneLucia Marucci
Jan 19, 2020·Tissue Engineering. Part B, Reviews·Steven James AveryRachel Jane Waddington
Apr 25, 2018·Biology Open·Arabella BairdDeborah J Guest
Jul 8, 2019·Environmental Science and Pollution Research International·Samira MahmoudiniaMohammad Mazani
Apr 5, 2020·International Journal of Molecular Sciences·Daniela RehakovaIrena Koutna
Apr 15, 2020·Life Science Alliance·Cristina AmeneiroMiguel Fidalgo
May 19, 2019·International Journal of Molecular Sciences·Evgeniya E BurkovaGeorgy A Nevinsky
Jul 18, 2017·International Journal of Molecular Medicine·Nianping ZhangDahong Long
Jul 2, 2016·In Vitro Cellular & Developmental Biology. Animal·Nimantana HeDongjun Liu
Sep 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Huizhen ShuWenxue Chen
Jun 11, 2019·Advanced Science·Tao BingDihua Shangguan
May 5, 2017·Journal of Photochemistry and Photobiology. B, Biology·Viktorija HercegAndrej Babič

❮ Previous
Next ❯

Methods Mentioned

BETA
phosphotransferase
PLAP
transfection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Rinsho byori. The Japanese journal of clinical pathology
T Ono, K Eto
Clinica Chimica Acta; International Journal of Clinical Chemistry
J Bergerman, S Blethen
Rinsho byori. The Japanese journal of clinical pathology
S IinoH Suzuki
© 2021 Meta ULC. All rights reserved