PMID: 6971701Mar 15, 1981Paper

Alkaline phosphatase positive lymphomas: a morphologic, immunologic, and enzymehistochemical study

Cancer
S PoppemaM R Halie

Abstract

Among 87 cases of different non-Hodgkin lymphomas studied with morphologic, enzymehistochemical, and immunologic techniques, ten were found with a positive alkaline phosphatase staining reaction of the cell membranes. The ages of the seven adult patients included in this report varied between 48-85 years. Studies of cell suspensions or cryostat sections demonstrated the presence of monoclonal membrane immunoglobulins indicating a B-cell origin of these lymphomas. Investigation of peripheral blood of six patients revealed the presence of a corresponding monoclonal lymphocyte population in four. According to Rappaport's classification, lymphoblastic, poorly differentiated, and well-differentiated lymphocytic as well as histiocytic lymphoma were encountered. According to the "Kiel" classification, most lymphomas were classified in the group of follicle-center cell tumors. The clinical course of the patients was variable. Non-Hodgkin lymphomas with alkaline phosphatase positive staining do not constitute a separate entity.

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Citations

Oct 30, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·D M Goldberg, D Brown
Jan 1, 1992·Veterinary Clinical Pathology·Rose E. Raskin, Marlin N. Nipper
Feb 1, 1988·Pathology, Research and Practice·J M EliasS Sabet
Apr 1, 1984·The Journal of Dermatologic Surgery and Oncology·H Kerl, H Kresbach
Apr 1, 1984·The Journal of Dermatologic Surgery and Oncology·M L GeertsO Braun-Falco
Nov 1, 1994·Veterinary Pathology·T TanimotoY Ohtsuki
Sep 1, 1988·European Journal of Haematology·M AbeH Wakasa

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