PMID: 858Oct 1, 1975

Alkaline phosphatases in human feces, intestinal mucosa and bile, and the occurrence of 5'-nucleotidase in feces (author's transl)

Zeitschrift Für Klinische Chemie Und Klinische Biochemie
V Benić, M Fiser-Herman

Abstract

Alkaline phosphatase (EC 3.1.3.1) in extracts of human feces resembles alkaline phosphatase in extracts of duodenal mucosa, except for its electrophoretic mobility in starch gel. It is very probable that the normal feces alkaline phosphatase derives from intestinal mucosa. Gall bladder alkaline phosphatase, which is markedly different, has not been found in normal feces. Some patients with acute viral hepatitis or protozoasis excrete an alkaline phosphatase which resembles gall bladder alkaline phosphatase and has the characteristics of 5'-nucleotidase (EC 3.1.3.5). The appearance of this enzyme correlates with low total alkaline phosphatase activity of the excreta.

Related Concepts

Alkaline Phosphatase
Biliary Sludge
Cholestasis
Molecular Sieve Chromatography
Feces
Gallbladder
Giardiasis
Hepatitis A
Hydrogen-Ion Concentration
Structure of Intestinal Gland

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