Alkamides from Phyllanthus fraternus

Planta medica
A A SittieS Brøgger Christensen

Abstract

Two alkamides E,E-2,4-octadienamide and E,Z-2,4-decadienamide have been isolated from Phyllanthus fraternus, a plant used in Ghanaian traditional medicine to treat malaria. The compounds possess an alpha, beta, gamma, delta-unsaturated conjugated amide, a feature believed to enhance antiplasmodial activity. By means of an in vitro assay the two alkamides have been shown to possess moderate antiplasmodial activity.

Citations

Mar 29, 2014·TheScientificWorldJournal·Bharti SarinAparajita Mohanty
Mar 10, 2016·Journal of Pharmacy & Bioallied Sciences·Abuzer AliMohammed Ali
Jun 5, 2012·Journal of Ethnopharmacology·Jente BoonenBart De Spiegeleer
May 21, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Xin MaoLan-Zhen Zhang
May 14, 2016·Parasitology Research·Gustav KomlagaPhilippe M Loiseau
Mar 19, 2014·Chemistry & Biodiversity·Weiyan QiKun Gao
Oct 20, 2020·Revista Brasileira De Farmacognosia : Orgão Oficial Da Sociedade Brasileira De Farmacognosia·Taiwo O ElufioyeAdeboye Adejare

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