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Alkylation of sulfhydryl groups on Galpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides

Biochimica Et Biophysica Acta

Jul 2, 2003

L GiustiM R Mazzoni

PMID: 12832082

Abstract

In rat striatum A(2A) adenosine receptors activate adenylyl cyclase through coupling to G(s)-like proteins, mainly G(olf) that is expressed at high levels in this brain region. In this study we report that the sulfhydryl alkylating reagent, N-ethylmaleimide (NEM), causes a concentration...read more

Mentioned in this Paper

Ethylmaleimide
Receptors, Purinergic P1
Tissue Membrane
Adenosine
Neostriatum
CGS 21680
Brain
Guanylyl Imidodiphosphate
Immune Sera
Fc Receptor
Paper Details
References
  • References12
  • Citations4
12
  • References12
  • Citations4

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Alkylation of sulfhydryl groups on Galpha(s/olf) subunits by N-ethylmaleimide: regulation by guanine nucleotides

Biochimica Et Biophysica Acta

Jul 2, 2003

L GiustiM R Mazzoni

PMID: 12832082

DOI:

Abstract

In rat striatum A(2A) adenosine receptors activate adenylyl cyclase through coupling to G(s)-like proteins, mainly G(olf) that is expressed at high levels in this brain region. In this study we report that the sulfhydryl alkylating reagent, N-ethylmaleimide (NEM), causes a concentration...read more

Mentioned in this Paper

Ethylmaleimide
Receptors, Purinergic P1
Tissue Membrane
Adenosine
Neostriatum
CGS 21680
Brain
Guanylyl Imidodiphosphate
Immune Sera
Fc Receptor

Similar Papers Found In These Feeds

Fc Receptors

Fc receptors (fcrs) mediate a plethora of biological functions as diverse as antigen presentation, phagocytosis, cytotoxicity, induction of inflammatory cascades and modulation of immune responses. Discover the latest research on Fc Receptors here.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

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Paper Details
References
  • References12
  • Citations4
12
  • References12
  • Citations4
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