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Alleles versus mutations: Understanding the evolution of genetic architecture requires a molecular perspective on allelic origins

Evolution; International Journal of Organic Evolution

Sep 17, 2015

David L Remington

Abstract

Perspectives on the role of large-effect quantitative trait loci (QTL) in the evolution of complex traits have shifted back and forth over the past few decades. Different sets of studies have produced contradictory insights on the evolution of genetic architecture. I argue that much of ...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Quantitative Trait Loci
Research
Scientific Study
Molecular Modeling
Recombination, Genetic
Adaptation
Alleles
EAF2
41
143
Paper Details
References
  • References91
  • Citations14
12345...
  • References91
  • Citations14
12

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Alleles versus mutations: Understanding the evolution of genetic architecture requires a molecular perspective on allelic origins

Evolution; International Journal of Organic Evolution

Sep 17, 2015

David L Remington

PMID: 26374707

DOI: 10.1111/evo.12775

Abstract

Perspectives on the role of large-effect quantitative trait loci (QTL) in the evolution of complex traits have shifted back and forth over the past few decades. Different sets of studies have produced contradictory insights on the evolution of genetic architecture. I argue that much of ...read more

Mentioned in this Paper

Genome-Wide Association Study
Study
Quantitative Trait Loci
Research
Scientific Study
Molecular Modeling
Recombination, Genetic
Adaptation
Alleles
EAF2
41
143

Similar Papers Found In These Feeds

Microbial Ecology, Genetics, and Evolution

Microbes may exist in a unicellular or colony form. Here is the latest research on their genetic makeup, their relationship with one another and the environment, and their evolution.

Microbial ecology, genetics and evolution

Microbes are microscopic organisms which may exist in a unicellular or colony form. Here is the latest research on their genetic makeup, their relationship with one another and the environment, and their evolution.

Related Papers

Trends in Genetics : TIG

Population genetics of genomics-based crop improvement methods

Trends in Genetics : TIGJanuary 14, 2011
Martha T HamblinJean-Luc Jannink
Paper Details
References
  • References91
  • Citations14
12345...
  • References91
  • Citations14
12
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