Allelic polymorphism of GIGANTEA is responsible for naturally occurring variation in circadian period in Brassica rapa

Proceedings of the National Academy of Sciences of the United States of America
Q XieC Robertson McClung

Abstract

GIGANTEA (GI) was originally identified by a late-flowering mutant in Arabidopsis, but subsequently has been shown to act in circadian period determination, light inhibition of hypocotyl elongation, and responses to multiple abiotic stresses, including tolerance to high salt and cold (freezing) temperature. Genetic mapping and analysis of families of heterogeneous inbred lines showed that natural variation in GI is responsible for a major quantitative trait locus in circadian period in Brassica rapa. We confirmed this conclusion by transgenic rescue of an Arabidopsis gi-201 loss of function mutant. The two B. rapa GI alleles each fully rescued the delayed flowering of Arabidopsis gi-201 but showed differential rescue of perturbations in red light inhibition of hypocotyl elongation and altered cold and salt tolerance. The B. rapa R500 GI allele, which failed to rescue the hypocotyl and abiotic stress phenotypes, disrupted circadian period determination in Arabidopsis. Analysis of chimeric B. rapa GI alleles identified the causal nucleotide polymorphism, which results in an amino acid substitution (S264A) between the two GI proteins. This polymorphism underlies variation in circadian period, cold and salt tolerance, and red light...Continue Reading

References

Sep 1, 1991·Molecular & General Genetics : MGG·M KoornneefJ H van der Veen
Jun 1, 1997·Journal of Biological Rhythms·J D PlautzS A Kay
Aug 2, 2000·Proceedings of the National Academy of Sciences of the United States of America·E HuqP H Quail
May 7, 2002·Trends in Plant Science·Mansour KarimiAnn Depicker
Jun 19, 2002·Proceedings of the National Academy of Sciences of the United States of America·Francisco J QuinteroJose M Pardo
Nov 8, 2003·Science·Todd P MichaelC Robertson McClung
Dec 14, 2006·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Neeraj SalathiaGraham J King
May 16, 2008·Plant Physiology·Patrice A SaloméC Robertson McClung
Nov 1, 2007·Plant Signaling & Behavior·María CrepyJorge J Casal
Jan 30, 2010·Science·H Charles J GodfrayCamilla Toulmin
Apr 13, 2010·BMC Plant Biology·Pauline StephensonLars Østergaard
Apr 22, 2010·Plant Physiology·Xiaodong XuC Robertson McClung
May 5, 2010·Proceedings of the National Academy of Sciences of the United States of America·Alexander GrafAlison M Smith
Mar 9, 2011·Proceedings of the National Academy of Sciences of the United States of America·Neil DalchauAlex A R Webb
Apr 21, 2011·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·P LouC R McClung
Jun 29, 2011·Proceedings of the National Academy of Sciences of the United States of America·Mariko Sawa, Steve A Kay
Aug 30, 2011·Nature Genetics·Xiaowu WangUNKNOWN Brassica rapa Genome Sequencing Project Consortium
Sep 20, 2011·Advances in Genetics·C Robertson McClung
Nov 23, 2011·Proceedings of the National Academy of Sciences of the United States of America·David TilmanBelinda L Befort
Sep 13, 2012·Frontiers in Plant Science·Feng ChengXiaowu Wang
Jul 11, 2013·PloS One·Deepak K RayJonathan A Foley
Jan 1, 2014·Trends in Plant Science·Polly Yingshan Hsu, Stacey L Harmer

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Citations

Oct 3, 2015·Journal of Experimental Botany·Kemal Kazan, Rebecca Lyons
Nov 26, 2019·American Journal of Botany·Brian J SandersonChristopher G Oakley
Dec 15, 2015·Annual Review of Plant Biology·Andrew J Millar
Jan 31, 2017·The New Phytologist·Eric J SedivyYoshie Hanzawa
Mar 1, 2017·The Plant Journal : for Cell and Molecular Biology·Faqiang WuYoshie Hanzawa
May 30, 2019·Cold Spring Harbor Perspectives in Biology·Nicky Creux, Stacey Harmer
Dec 19, 2019·Frontiers in Genetics·Paige E PanterAntony N Dodd
Nov 15, 2019·Plant, Cell & Environment·Yu WangQiguang Xie
Oct 2, 2020·Genes·Claudio BrandoliJulia Weiss
Jun 21, 2018·Frontiers in Plant Science·Ben Trevaskis
Mar 14, 2018·The New Phytologist·Jihua DingOve Nilsson
Apr 18, 2018·Plant, Cell & Environment·Yulia YarkhunovaCynthia Weinig
Feb 23, 2020·Plant Science : an International Journal of Experimental Plant Biology·Atsushi OdaTamotsu Hisamatsu
Feb 14, 2019·G3 : Genes - Genomes - Genetics·Matthew J RubinCynthia Weinig
Mar 30, 2021·The New Phytologist·Kathleen K Markham, Kathleen Greenham

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