Allelic variants of the Pseudomonas syringae type III effector HopZ1 are differentially recognized by plant resistance systems

Molecular Plant-microbe Interactions : MPMI
Huanbin ZhouWenbo Ma

Abstract

The bacterial plant pathogen Pseudomonas syringae depends on the type III secretion system and type III-secreted effectors to cause disease in plants. HopZ is a diverse family of type III effectors widely distributed in P. syringae isolates. Among the HopZ homologs, HopZ1 is ancient to P. syringae and has been shown to be under strong positive selection driven by plant resistance-imposed selective pressure. Here, we characterized the virulence and avirulence functions of the three HopZ1 alleles in soybean and Nicotiana benthamiana. In soybean, HopZ1 alleles have distinct functions: HopZ1a triggers defense response, HopZ1b promotes bacterial growth, and HopZ1c has no observable effect. In N. benthamiana, HopZ1a and HopZ1b both induce plant defense responses. However, they appear to trigger different resistance pathways, evidenced by two major differences between HopZ1a- and HopZ1b-triggered hypersensitive response (HR): i) the putative N-acylation sites had no effect on HopZ1a-triggered cell death, whereas it greatly enhanced HopZ1b-triggered cell death; and ii) the HopZ1b-triggered HR, but not the HopZ1a-triggered HR, was suppressed by another HopZ homolog, HopZ3. We previously demonstrated that HopZ1a most resembled the ancest...Continue Reading

References

Sep 21, 1979·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·R Dawkins, J R Krebs
Jun 1, 1987·Journal of Bacteriology·M J HickmanN J Panopoulos
Jul 1, 1995·Molecular Plant-microbe Interactions : MPMI·Y Yang, D W Gabriel
Jul 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·E V SokurenkoD L Hasty
Jun 4, 1999·Trends in Microbiology·E V SokurenkoD E Dykhuizen
Jun 30, 2000·Current Opinion in Plant Biology·E A Stahl, J G Bishop
Nov 15, 2000·Proceedings of the National Academy of Sciences of the United States of America·M B MudgettB J Staskawicz
Feb 24, 2001·Plant Molecular Biology·M C Heath
Jul 19, 2001·Nature·J L Dangl, J D Jones
Aug 24, 2001·Biological Chemistry·A J Barrett, N D Rawlings
Feb 8, 2002·Trends in Plant Science·Renier A L Van der HoornMatthieu H A J Joosten
Oct 9, 2002·Molecular Microbiology·Boris SzurekUlla Bonas
Feb 6, 2004·The Plant Journal : for Cell and Molecular Biology·Yashitola JamirJames R Alfano
Jun 1, 1997·Annual Review of Plant Physiology and Plant Molecular Biology·Jean T. Greenberg
Mar 31, 2004·Trends in Microbiology·Sebastian Maurer-Stroh, Frank Eisenhaber
Apr 7, 2004·Applied and Environmental Microbiology·Sara F Sarkar, David S Guttman
Jun 24, 2004·Infection and Immunity·James R Bretz, Steven W Hutcheson
Jul 3, 2004·Current Opinion in Plant Biology·Andrew Hotson, Mary Beth Mudgett
Jul 31, 2004·Annual Review of Phytopathology·James R Alfano, Alan Collmer
Nov 18, 2004·Biochimica Et Biophysica Acta·Sheng Yang HeThomas S Whittam
Dec 14, 2004·Science·Rebecca L AllenJim L Beynon
Dec 16, 2004·Molecular Plant-microbe Interactions : MPMI·Alison E RobertsonDaniel A Kluepfel
Dec 20, 2005·Current Biology : CB·Andrew R PitmanDawn L Arnold
Dec 22, 2005·The Plant Journal : for Cell and Molecular Biology·Jeroen S de VriesJohn P Rathjen

❮ Previous
Next ❯

Citations

Feb 5, 2013·Nature Genetics·Yongli QiaoWenbo Ma
Feb 10, 2012·PLoS Pathogens·Amy Huei-Yi LeeDarrell Desveaux
Jun 26, 2012·Annual Review of Microbiology·James D BeverElise R Morton
Jan 14, 2011·Current Opinion in Microbiology·Anna Block, James R Alfano
Jul 20, 2010·The New Phytologist·Alberto P MachoCarmen R Beuzón
Jul 6, 2011·Molecular Plant Pathology·Jennifer D LewisDarrell Desveaux
Oct 2, 2009·Plant Signaling & Behavior·Shuguo HouJian-Min Zhou
Jul 17, 2012·Trends in Plant Science·Laurent Deslandes, Susana Rivas
Mar 16, 2011·Cell Host & Microbe·Andrew Bent
Nov 25, 2011·FEMS Microbiology Letters·Christos T FotiadisAnastasia P Tampakaki
May 12, 2016·Seminars in Cell & Developmental Biology·Karl J SchreiberJennifer D Lewis
Jul 1, 2016·Annual Review of Phytopathology·Steven A WhithamTarek Hewezi
Apr 22, 2018·Applied and Environmental Microbiology·Mustafa O JibrinErica M Goss
Oct 28, 2016·Microbiology and Molecular Biology Reviews : MMBR·Ka-Wai Ma, Wenbo Ma
Aug 30, 2018·Frontiers in Plant Science·José S RufiánJavier Ruiz-Albert
Jun 14, 2019·Frontiers in Plant Science·Liyuan ZhangHansong Dong
Aug 8, 2021·International Journal of Molecular Sciences·Fernando Sanz-GarcíaSara Hernando-Amado

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.