Apr 12, 1991

Allergenic fragments in Parietaria judaica pollen extract

Journal of Chromatography
E BolzacchiniI Sondergaard

Abstract

High-performance ion-exchange chromatography and immunoaffinity chromatography suggest that Par jI, the principal allergenic component of Parietaria judaica pollen, is a very unstable molecule, which tends to fragment in solution. Several fragments were obtained from Par jI and some of them show positivity toward the anti-Par jI monoclonal antibody, suggesting that they retain the entire structure of the allergenic determinant. These fragments could be the target for sequence and conformation studies.

  • References1
  • Citations10

References

Mentioned in this Paper

Parietaria judaica pollen
Monoclonal Antibodies
Antigenic Specificity
Radioallergosorbent Test
Allergens
Immunoaffinity Chromatography
High Pressure Liquid Chromatography Procedure
Antibody Dissociation
Drug Stability
Ion-Exchange Chromatography Procedure

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