PMID: 2580878May 1, 1985Paper

Allergens in Hymenoptera venom XV: The immunologic basis of vespid venom cross-reactivity

The Journal of Allergy and Clinical Immunology
D R Hoffman


RAST-inhibition studies were performed by use of whole venom sac extracts to inhibit binding to purified venom allergens from various vespid wasps. Immunodiffusion studies were also performed with rabbit antisera raised against purified venom proteins. Immunologic cross-reactivity was demonstrated among the hyaluronidases, phospholipases, and antigen 5 s from both subgenera of yellow jackets, white-faced hornets, and paper wasps. The paper wasp hyaluronidase and antigen 5 were less related to those of the other three species than those of yellow jackets and hornets. It appears that immunologic cross-reactivity is the major mechanism of multiple allergic sensitivity to vespid venoms. Therapy with only the primary venom should be sufficient to protect against reactions from cross-reacting venoms.


May 1, 1995·Toxicon : Official Journal of the International Society on Toxinology·O CasconeL E Díaz
Sep 1, 1986·The Journal of Allergy and Clinical Immunology·N A MarshallA Saxon
Nov 1, 1988·The Journal of Allergy and Clinical Immunology·D R HoffmanC T Stafford
Oct 24, 2003·Biochimica Et Biophysica Acta·Barbara PanteraLuigia Pazzagli
Feb 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·K S FangT P King
Apr 7, 2009·Journal of Proteomics·Dirk C de GraafBart Devreese
Dec 1, 2007·Allergologia et immunopathologia·A J Pérez PimientoE Calvo Manuel
Oct 4, 2005·Allergy·B M BilóUNKNOWN EAACI Interest Group on Insect Venom Hypersensitivity
Jun 24, 2006·Allergy·M G SeverinoF Bonifazi
Aug 19, 2004·The Journal of Allergy and Clinical Immunology·Jeffrey S NugentTheodore M Freeman
Mar 7, 2014·Toxicon : Official Journal of the International Society on Toxinology·Débora Laís Justo JacominiMárcia Regina Brochetto Braga
Jun 26, 2015·Current Opinion in Allergy and Clinical Immunology·James M TracyJohn Carlson
Nov 24, 1999·The Veterinary Clinics of North America. Small Animal Practice·D E Bevier
Jun 1, 1993·Postgraduate Medicine·J E MoffittC T Stafford
Jul 11, 2020·Current Allergy and Asthma Reports·Simon BlankThilo Jakob
May 23, 2021·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·John C Carlson, Mark S Fox

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.