Allergic contact dermatitis caused by titanium screws and dental implants

Journal of Prosthodontic Research
Maki HosokiYoshizo Matsuka

Abstract

Titanium has been considered to be a non-allergenic material. However, several studies have reported cases of metal allergy caused by titanium-containing materials. We describe a 69-year-old male for whom significant pathologic findings around dental implants had never been observed. He exhibited allergic symptoms (eczema) after orthopedic surgery. The titanium screws used in the orthopedic surgery that he underwent were removed 1 year later, but the eczema remained. After removal of dental implants, the eczema disappeared completely. Titanium is used not only for medical applications such as plastic surgery and/or dental implants, but also for paints, white pigments, photocatalysts, and various types of everyday goods. Most of the usage of titanium is in the form of titanium dioxide. This rapid expansion of titanium-containing products has increased percutaneous and permucosal exposure of titanium to the population. In general, allergic risk of titanium material is smaller than that of other metal materials. However, we suggest that pre-implant patients should be asked about a history of hypersensitivity reactions to metals, and patch testing should be recommended to patients who have experienced such reactions.

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Citations

Oct 18, 2016·International Journal of Implant Dentistry·Marcelo Augusto Pinto Cardoso GoularteLuciana Mayumi Hirakata
Jun 25, 2016·Journal of Prosthodontic Research·Masaru Kaku
Oct 25, 2016·Journal of Prosthodontic Research·Kenji Fueki
Sep 15, 2016·Journal of Dental Research·S PieralliB C Spies
Dec 6, 2019·Macromolecular Bioscience·Jennifer KnausHelmut Cölfen
Feb 11, 2019·Journal of Prosthodontic Research·Masae KitagawaHidemi Kurihara
Aug 25, 2017·Dental Materials Journal·Chikahiro OhkuboYasunori Suzuki
Jul 2, 2020·Progress in Orthodontics·Martina ZiganteStjepan Spalj
Mar 12, 2019·International Journal of Implant Dentistry·Kyeong Tae KimSoung Min Kim
Jan 5, 2021·Clinical Implant Dentistry and Related Research·Reydson Alcides de Lima-SouzaMaria Letícia Cintra
Nov 30, 2019·Endocrine, Metabolic & Immune Disorders Drug Targets·Thea MagroneEmilio Jirillo
Nov 22, 2020·Biology·Rubén Comino-GarayoaMaría Jesús Suárez
May 7, 2021·Case Reports in Dentistry·Ali Robaian AlqahtaniJia Chang
Jun 15, 2021·BioMed Research International·Radka VrbovaAlex Vinsu
Aug 3, 2021·Clinical Reviews in Allergy & Immunology·Zhouxian PanJing Zhang
Nov 23, 2021·Dermatitis : Contact, Atopic, Occupational, Drug·Ghazal GhafariWalter Liszewski

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