Allergic contact dermatitis from allyl isothiocyanate in a Danish cohort of 259 selected patients

Contact Dermatitis
Anne LerbaekT Menné

Abstract

Allyl isothiocyanate is present in many plants. Allergic contact dermatitis from allyl isothiocyanate is well known but infrequently reported. The aim of this study was to investigate the prevalence of contact allergy to allyl isothiocyanate in patients with suspected contact dermatitis from vegetables and food. 259 such patients were tested at the Department of Dermatology, Gentofte Hospital, Denmark, from 1994 to 2003. Only 2 patients (0.8%) had a positive reaction (+) to allyl isothiocyanate and 43 patients (16.6%) had a ?+ reaction. One of the patients with a positive reaction provided samples of margarine, salad cream, oil and mayonnaise. These were analysed with high-performance liquid chromatography, and a moderate concentration of allyl isothiocyanate (2.5 ppm) was detected in the sample of margarine. This patient was a professional sandwich maker presenting with fingertip dermatitis mimicking 'tulip fingers' or allergic contact dermatitis from garlic and onions. In conclusion, allergic contact dermatitis from allyl isothiocyanate occurs in only a limited number of cases, despite frequent exposure. The large number of ?+ reactions raises the question as to whether the recommended patch test concentration is too low.

References

Oct 1, 1975·Contact Dermatitis·W G van Ketel
Feb 1, 1976·Contact Dermatitis·N Hjorth, J Roed-Petersen
Sep 1, 1990·Contact Dermatitis·P K Kohl, P J Frosch
Apr 1, 1987·Contact Dermatitis·C J Dannaker, I R White
Sep 1, 1987·Contact Dermatitis·G Kavli, D Moseng
Aug 1, 1985·Contact Dermatitis·B Meding
Aug 1, 1974·The British Journal of Dermatology·J C Mitchell, W P Jordan
Jun 1, 1996·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·M BruzeA C Hellström
Aug 5, 1998·Allergy·I M Sánchez-Guerrero, A I Escudero
Mar 11, 1999·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·U JappeH Gollnick
Aug 12, 1999·American Journal of Contact Dermatitis : Official Journal of the American Contact Dermatitis Society·T W McGovern
Sep 13, 2001·Contact Dermatitis·S D MorrisR J Rycroft
Jan 22, 2003·The British Journal of Dermatology·A ChakrabartiI S Foulds
Aug 1, 1964·Archives of Dermatology·L E GAUL

❮ Previous
Next ❯

Citations

Jul 16, 2014·International Journal of Critical Illness and Injury Science·James McCluskeyRaymond Harbison
Apr 14, 2012·Journal of Biomedicine & Biotechnology·Ori ScottJerome Y Yager
May 4, 2018·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·A BauerV Mahler
Apr 2, 2021·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Sumiko AbeKazuhisa Takahashi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Contact Dermatitis
W BroeckxG Achten
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
A LapczynskiA M Api
© 2021 Meta ULC. All rights reserved