PMID: 18413109Apr 17, 2008Paper

Allergic contact dermatitis in children: the Ottawa hospital patch-testing clinic experience, 1996 to 2006

Dermatitis : Contact, Atopic, Occupational, Drug
Marcia Hogeling, Melanie Pratt

Abstract

Allergic contact dermatitis in children is a significant clinical problem. Patch testing is a diagnostic tool for the evaluation of patients with suspected allergic contact dermatitis. To determine the frequency and relevance of positive patch-test results in children and to identify the most common allergens in children at our clinic. Retrospective chart review of 100 children and adolescents, aged 4 to 18 years, who were patch-tested at the Ottawa Hospital patch-testing clinic between 1996 and 2006. The children were patch-tested with the North American Contact Dermatitis Group (NACDG) standard series, supplementary series if indicated, and their own products if available. Seventy percent of children had at least one positive patch-test reaction; 55.8% of positive patch-test reactions were relevant. The ratio of females to males was 62:38. The most common allergens were nickel sulfate (26%), cobalt (14%), fragrance mix (7%), neomycin (7%), colophony (6%), formaldehyde (4%), lanolin (4%), quaternium-15 (4%), and para-phenylenediamine (4%). Nickel co-reacted with cobalt (68%) and palladium (100%). Of children tested, 41% had a history of atopic dermatitis. The frequency of positive and relevant allergens in children is similar ...Continue Reading

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