PMID: 9192218Jan 1, 1997Paper

Allergic disease, immunoglobulins, exposure to mercury and dental amalgam in Swedish adolescents

International Archives of Occupational and Environmental Health
P HerrströmL Råstam

Abstract

High-dose exposure to inorganic mercury in man can influence the immune system and in rare cases cause immune-related disease. Some experimental animals also react with autoimmunity after low doses of inorganic mercury. Glomerulonephritis and an increased formation of immunoglobulin type E (IgE) are characteristic of these reactions. A recent study of 15-year-old adolescents demonstrated an association between immunoglobulin type A (IgA) and mercury concentration in plasma (P-Hg). There was also an association between allergic disease and IgA levels. The present study included 54 male and 23 female 19-year-old students who were recruited from a cohort that had been previously defined in a survey of allergic disease. Of the students, 39 (51%) had asthma, allergic rhinoconjunctivitis or eczema. Similar amalgam burden and P-Hg levels were observed in students with (n = 39) and without (n = 38) allergic disease (P = 0.48 and P = 0.98, respectively). As expected, IgE levels were significantly higher in the group with allergic disease (P = 0.006), but there was no association between P-Hg and IgE. The P-Hg levels were very low (median 1.50 nmol/l) and correlated significantly (r = 0.31) with the small number of amalgam surfaces (P = ...Continue Reading

Citations

Jun 12, 2003·The Science of the Total Environment·Per HerrströmBenkt Högstedt
Jul 10, 1999·Journal of Dentistry·C J WhittersD Wood
Mar 15, 2005·Journal of Toxicology and Environmental Health. Part a·Cecilia JohnssonGerd Sällsten
Aug 27, 2002·Environmental Health Perspectives·George D Leikauf
Feb 2, 2006·International Journal of Hygiene and Environmental Health·Michael N Bates
Jul 11, 2016·The Journal of Allergy and Clinical Immunology·Sangshin ParkYounglim Kho

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.