Allergic diseases and atopic sensitization in children related to farming and anthroposophic lifestyle--the PARSIFAL study

Allergy
T AlfvénPARSIFAL Study Group

Abstract

The prevalence of allergic diseases has increased rapidly in recent decades, particularly in children. For adequate prevention it is important not only to identify risk factors, but also possible protective factors. The aim of this study was to compare the prevalence of allergic diseases and sensitization between farm children, children in anthroposophic families, and reference children, with the aim to identify factors that may protect against allergic disease. The study was of cross-sectional design and included 14,893 children, aged 5-13 years, from farm families, anthroposophic families (recruited from Steiner schools) and reference children in Austria, Germany, The Netherlands, Sweden and Switzerland. A detailed questionnaire was completed and allergen-specific IgE was measured in blood. Growing up on a farm was found to have a protective effect against all outcomes studied, both self-reported, such as rhinoconjunctivitis, wheezing, atopic eczema and asthma and sensitization (allergen specific IgE > or = 0.35 kU/l). The adjusted odds ratio (OR) for current rhinoconjunctivitis symptoms was 0.50 (95% confidence interval (CI) 0.38-0.65) and for atopic sensitization 0.53 (95% CI 0.42-0.67) for the farm children compared to the...Continue Reading

References

Mar 1, 1995·The European Respiratory Journal·M I AsherA W Stewart
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S A Lewis
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·O S Von EhrensteinR von Kries
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J RiedlerM Schreuer
Jan 29, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·M KilpeläinenM Koskenvuo
Sep 6, 2000·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·E von MutiusD Nowak
Aug 9, 2001·The European Respiratory Journal·B KlintbergM van Hage-Hamsten
Dec 12, 2001·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·B FilipiakH E Wichmann
Sep 20, 2002·The New England Journal of Medicine·Charlotte Braun-FahrländerUNKNOWN Allergy and Endotoxin Study Team
Oct 3, 2002·American Journal of Respiratory and Critical Care Medicine·Ulrike GehringJoachim Heinrich
Apr 12, 2003·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·C Braun-Fahrländer, R Lauener
Apr 12, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Magnus WickmanS Lennart Nordvall
Feb 7, 2004·Allergy·L C Von Hertzen, T Haahtela
Apr 7, 2004·The European Respiratory Journal·C Braun-FahrländerUNKNOWN Air Pollution (SCARPOL) team
Aug 10, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K RadonD Nowak

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Citations

Aug 20, 2010·Current Allergy and Asthma Reports·Petri S Mattila
Jun 25, 2013·Preventive Veterinary Medicine·Neil Pearce, Jeroen Douwes
Apr 10, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Einat YaariEitan Kerem
Sep 1, 2007·The British Journal of Nutrition·Ischa KummelingPieter C Dagnelie
Apr 16, 2013·Journal of Agricultural and Food Chemistry·Maja Melballe JensenCharlotte Lauridsen
May 9, 2012·Nature Medicine·Stephen T Holgate
Nov 10, 2010·Nature Reviews. Immunology·Erika von Mutius, Donata Vercelli
Feb 25, 2011·The New England Journal of Medicine·Markus J EgeUNKNOWN GABRIELA Transregio 22 Study Group
Jan 31, 2012·International Journal of Epidemiology·Bert BrunekreefUNKNOWN ISAAC Phase Three Study Group
Mar 6, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Li-Xing Man
Feb 13, 2007·Applied and Environmental Microbiology·Johan DicksvedJanet K Jansson
Oct 5, 2006·Occupational and Environmental Medicine·Lidwien A M SmitJeroen Douwes
Jun 19, 2007·American Journal of Respiratory and Critical Care Medicine·Gudrun WeinmayrUNKNOWN ISAAC Phase Two Study Group
Mar 27, 2007·American Journal of Respiratory and Critical Care Medicine·Wendy C Moore, Stephen P Peters
Mar 8, 2014·PloS One·Remo FreiUNKNOWN as part of the PARSIFAL study team
Dec 20, 2013·International Journal of Environmental Research and Public Health·John MolloyPeter Vuillermin
Jul 14, 2010·International Journal of Environmental Research and Public Health·Jimmy T Efird
May 4, 2013·European Journal of Public Health·Ana Paula Simões-WüstCarel Thijs
Oct 22, 2013·Occupational and Environmental Medicine·Lidwien A M SmitDick Heederik
Dec 18, 2010·Revue des maladies respiratoires·M Hulin, I Annesi-Maesano
Aug 3, 2014·International Immunopharmacology·Adam D WellsDebra J Romberger
Nov 9, 2007·Seminars in Immunopathology·Kevin Tse, Anthony A Horner
Jan 21, 2016·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Javen Wunschel, Jill A Poole
May 19, 2010·Expert Review of Clinical Immunology·Jeroen DouwesNeil Pearce
Apr 11, 2014·International Journal of Environmental Research and Public Health·Eva JohanssonMarie E Olsson
Feb 21, 2016·BMC Family Practice·Christel E van DijkC Joris Yzermans
Jul 9, 2008·Annals of Medicine·Alexandros P Grammatikos
Aug 1, 2012·The Journal of Allergy and Clinical Immunology·Georg LossUNKNOWN PASTURE study group
Apr 24, 2012·The Journal of Allergy and Clinical Immunology·Caroline RoduitUNKNOWN Protection Against Allergy–Study in Rural Environments study group
Jan 24, 2012·Seminars in Fetal & Neonatal Medicine·A John Henderson, John O Warner
Oct 7, 2011·The Journal of Allergy and Clinical Immunology·Katja WarmEva Rönmark
Mar 1, 2011·The Journal of Allergy and Clinical Immunology·Aline NaumannStephan Weidinger
Jun 29, 2010·Psychoneuroendocrinology·Fredrik SteniusTöres Theorell
Mar 10, 2010·Experimental Cell Research·Erika Rindsjö, Annika Scheynius
Sep 23, 2008·The Journal of Allergy and Clinical Immunology·Jennifer S KimXiaobin Wang
Jul 16, 2008·The Journal of Allergy and Clinical Immunology·Donata Vercelli
Aug 6, 2008·The Journal of Allergy and Clinical Immunology·Markus Johannes EgeUNKNOWN Protection Against Allergy Study in Rural Environments (PASTURE) Study group
Jun 24, 2008·Immunology and Allergy Clinics of North America·Erika von Mutius, Katja Radon
Oct 9, 2007·The Journal of Allergy and Clinical Immunology·Christian BieliUNKNOWN PARSIFAL study group
Mar 14, 2007·The Journal of Allergy and Clinical Immunology·Markus Johannes EgeUNKNOWN PARSIFAL Study team

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