Allergy to kiwi in patients with baker's asthma: identification of potential cross-reactive allergens

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Arantxa PalacinG Salcedo

Abstract

Baker's asthma is a frequent IgE-mediated occupational disorder mainly provoked by inhalation of cereal flour. Allergy to kiwifruit has being increasingly reported in the past few years. No association between both allergic disorders has been described so far. Twenty patients with occupational asthma caused by wheat flour inhalation were studied. Kiwi allergens Act d 1 and Act d 2 were purified by cation-exchange chromatography. Wheat, rye, and kiwi extracts, purified kiwi allergens, and model plant glycoproteins were analyzed by IgE immunodetection, enzyme-linked immunosorbent assay (ELISA), and inhibition ELISAs. Kiwifruit ingestion elicited oral allergy syndrome in 7 of the 20 patients (35%) with baker's asthma. Positive specific IgE and skin prick test responses to this fruit were found in all these kiwi allergic patients, and IgE to Act d 1 and Act d 2 was detected in 57% and 43%, respectively, of the corresponding sera. Actinidin Act d 1 and bromelain (harboring cross-reactive carbohydrate determinants) reached above 50% inhibition of the IgE binding to wheat and/or kiwi extracts. A potential association between respiratory allergy to cereal flour and allergy to kiwifruit has been disclosed. Cross-reactive carbohydrate de...Continue Reading

References

May 1, 1977·Clinical Allergy·W B KlaustermeyerF C Hale
Dec 1, 1992·The Journal of Allergy and Clinical Immunology·S QuirceE Losada
Dec 31, 1997·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·R Sánchez-MongeG Salcedo
May 9, 1998·The Journal of Allergy and Clinical Immunology·E A PastorelloC Ortolani
Sep 14, 1999·The Journal of Allergy and Clinical Immunology·A Diaz-PeralesG Salcedo
Jul 11, 2002·Occupational and Environmental Medicine·Jonas Brisman
Jan 25, 2003·Current Allergy and Asthma Reports·Carlos Blanco
Sep 19, 2003·The Journal of Allergy and Clinical Immunology·Gloria García-CasadoGabriel Salcedo
Dec 17, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Jane S A LucasJonathan O'B Hourihane
Jul 14, 2004·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J S A LucasJ O'B Hourihane
Nov 13, 2004·The Journal of Allergy and Clinical Immunology·Merima BublinChristian Radauer
Mar 9, 2006·The Journal of Allergy and Clinical Immunology·Michael WeichelReto Crameri
Oct 13, 2006·International Archives of Allergy and Immunology·Friedrich Altmann
Aug 24, 2007·Internal Medicine Journal·S Swaminathan, R J Heddle
Aug 25, 2007·The Journal of Allergy and Clinical Immunology·Arantxa PalacinGabriel Salcedo
Sep 12, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J S A LucasJ O'b Hourihane
Jan 22, 2008·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·A PalacinG Salcedo

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Citations

Aug 11, 2011·PloS One·Tania DottoriniAndrea Crisanti
Feb 7, 2014·Current Opinion in Allergy and Clinical Immunology·Santiago Quirce
Aug 29, 2013·Molecular Nutrition & Food Research·Esther Muñoz-GarcíaCarlos Pastor-Vargas
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·Imran PashaWaqas Ahmed
Jun 23, 2015·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·H HowarthM Jones
Nov 2, 2013·Allergy, Asthma & Immunology Research·Santiago Quirce, Araceli Diaz-Perales
Jul 21, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S Quirce, G Salcedo
Aug 5, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·J Sastre
Mar 19, 2019·Current Opinion in Allergy and Clinical Immunology·Yuma Fukutomi

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