Allogeneic and xenogeneic grafts in pulmonate gastropod molluscs: fates of neural transplants

Developmental and Comparative Immunology
A Gomot, L Gomot

Abstract

Neural intracerebral allo- and xenografts in pulmonate gastropods demonstrated a variation in the tolerance of neural xenogeneic grafts that was dependent on the phylogenetic distance between the donor and the host. Like allografts, neural congeneric xenografts (Hp/Haa and H1/Haa) of cerebral ganglia (CG) were tolerated and restored growth in juvenile mesocerebrum-deprived (Haa) snails. However, CG neural xenografts between different genera of stylommatophorans (Achatina fulica/Haa) or between genera of different orders (Lymnaea stagnalis: Basommatophora/Haa: Stylommatophora) revealed an interspecific histoincompatibility. These results, compared with those described by other authors, suggest that gastropods possess mechanisms for the recognition of non-self that depend on the organ considered and the phylogenetic distance separating host and donor. Research should now attempt to identify the factors responsible for graft destruction.

References

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Citations

Jun 12, 2003·Tissue & Cell·Gianluca TettamantiMagda de Eguileor
May 1, 2013·Developmental Neurobiology·Ryota MatsuoEtsuro Ito
Jun 1, 2013·Developmental Neurobiology·Ryota MatsuoEtsuro Ito
Feb 3, 1998·Journal of Invertebrate Pathology·J T SullivanR R Lares
Jun 22, 2000·Microscopy Research and Technique·S B Moffett

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