PMID: 9551335Apr 29, 1998Paper

Allopurinol as an inducer of acute graft-versus-host-like drug reaction. Case report with review of the literature

Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
U JappeH Gollnick

Abstract

Although drug eruptions resembling graft-versus-host disease are rare, GvH-like reactions to the sulfhydryl group of drugs (penicillamine, captopril, gold sodium), phenobarbital and hepatitis vaccine have been described. Clinical reports concerning acute GvH-like drug rash are very uncommon and restricted to acetylsalicylic acid and spironolactone. We report on a patient who developed an acute GvH-like drug reaction caused by allopurinol. To our knowledge this variant of cytotoxic drug eruption has not yet been reported in literature.

Citations

Jul 23, 2013·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Sheena N RamasamyRichard O Day

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