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Alpha 1-adrenoceptors of rat myocardium: comparison of agonist binding and positive inotropic response

Naunyn-Schmiedeberg's Archives of Pharmacology

Nov 1, 1988

G GrossC Rugevics

Abstract

Binding of agonists to alpha 1-adrenoceptors labelled by 3H-prazosin was investigated in membranes of rat myocardium and compared to the inotropic response elicited by alpha 1-adrenoceptor activation on isolated right ventricles. 1. At 30 degrees C the full agonists, adrenaline and phen...read more

Mentioned in this Paper

Epinephrine Measurement
Metabolic Inhibition
Metaplastic Cell Transformation
V-Serp
Right Ventricular Structure
Tissue Membrane
Phenoxybenzamine Hydrochloride
Agonists
Indanidine
Methoxamine
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Alpha 1-adrenoceptors of rat myocardium: comparison of agonist binding and positive inotropic response

Naunyn-Schmiedeberg's Archives of Pharmacology

Nov 1, 1988

G GrossC Rugevics

PMID: 2907612

DOI: 10.1007/bf00179334

Abstract

Binding of agonists to alpha 1-adrenoceptors labelled by 3H-prazosin was investigated in membranes of rat myocardium and compared to the inotropic response elicited by alpha 1-adrenoceptor activation on isolated right ventricles. 1. At 30 degrees C the full agonists, adrenaline and phen...read more

Mentioned in this Paper

Epinephrine Measurement
Metabolic Inhibition
Metaplastic Cell Transformation
V-Serp
Right Ventricular Structure
Tissue Membrane
Phenoxybenzamine Hydrochloride
Agonists
Indanidine
Methoxamine

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Paper Details
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  • Citations8
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