Dec 15, 1980

Alpha 1-antitrypsin and alpha 2-macroglobulin do not inhibit the kinin-releasing activity of kallikreins from human urine and saliva

Biochimica Et Biophysica Acta
W Sakamoto, O Nishikaze

Abstract

Alpha 1-Antitrypsin, alpha 2-macroglobulin and low-molecular weight kininogen were isolated from human serum and kallikreins from human urine and saliva. Alpha 1-antitrypsin and alpha 2-macroglobulin inhibited the activity of trypsin in releasing kinin from low-molecular weight kininogen, due to their binding with the enzyme, but did not inhibit or bind with urinary and salivary kallikreins.

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Mentioned in this Paper

KNG1
Alpha 1-Acute Phase Globulin
Human urine
Kininogen
Saliva - SpecimenType
Kinins
Trypsin
Alpha 2-Glucoproteins
Saliva
Alpha 1-Antitrypsin

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