PMID: 6161646Nov 20, 1980Paper

alpha 1-Microglobulin from normal and pathological urines

Biochimica Et Biophysica Acta
I BernierP Jollès

Abstract

alpha 1-Microglobulin was purified from normal and pathological urines. Significant differences were found in the amino acid compositions of the alpha 1-microglobulin isolated from these two sources. In addition electrofocusing of alpha 1-microglobulin from normal urine gave rise to two peaks of equal intensity with rather acidic isoelectric points (3.8 and 4.2), whilst alpha 1-microglobulin from pathological urine showed two peaks in a 1:5 ratio with less acidic isoelectric points (4.2 and 4.7). Further charge heterogeneity was also observed in the second peaks from both sources. The sugar compositions were also established, as well as the N-terminal sequences of the alpha 1-microglobulin of both peaks isolated from normal and pathological urines.

References

Aug 18, 1975·Biochemical and Biophysical Research Communications·B EkströmI Berggård
Feb 1, 1979·The Journal of Clinical Investigation·K TakagiT Shikata
Apr 26, 1978·Biochimica Et Biophysica Acta·I BernierP Jollès
Nov 1, 1976·FEBS Letters·B FrangioneL Tejler
Dec 1, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·L Svensson, U Ravnskov
Mar 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·C TerhorstJ L Strominger
May 1, 1975·European Journal of Biochemistry·J Jollès, P Jollès
Jan 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation. Supplementum·C B Laurell
May 1, 1974·Thorax·L J Temple
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans

❮ Previous
Next ❯

Citations

Jun 25, 2013·Clinical and Experimental Medicine·Nicolas R RoblesJuan J Cubero
Apr 1, 1991·Molecular Immunology·B AkerströmG Lindahl
Jul 1, 1990·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M D DonaldsonJ T Whicher
Nov 4, 2000·Biochimica Et Biophysica Acta·B AkerströmA Lindqvist
Jul 17, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Joris Penders, Joris R Delanghe

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.