PMID: 37973Aug 1, 1978

Alpha-adrenergic agents in urinary disorders of the proximal urethra. Part II. Urethral obstruction due to "sympathetic dyssynergia"

British Journal of Urology
S A AwadH G Kiruluta

Abstract

Lower urinary tract obstruction in patients with neurological lesions can be due to "sympathetic dyssynergia". The obstruction can be at the level of the external sphincter. Phentolamine (i.v.) used during the voiding cystourethrogram helps to make the diagnosis. Phenoxybenzamine therapy produced improvement in 10 of 18 patients. As a rule, patients had to continue on the drug to maintain their response.

References

Alpha-adrenergic agents in urinary disorders of the proximal urethra. Part I. Sphincteric incontinence

Aug 1, 1978·British Journal of Urology·S A AwadH G Kiruluta

Alpha-adrenolytic treatment of the congenital neuropathic bladder

Jan 1, 1975·Urologia Internationalis·K Stockamp, F Schreiter

The phentolamine test in neurogenic bladder dysfunction

Apr 1, 1977·The Journal of Urology·C A OlssonR J Krane

Light and electron microscopic observations on noradrenergic nerves and striated muscle cells of the guinea pig urethra

May 1, 1977·The American Journal of Anatomy·J S Dixon, J A Gosling

Sympathetic dyssynergia in the region of the external sphincter: a possible source of lower urinary tract obstruction

Oct 1, 1977·The Journal of Urology·S A Awad, J W Downie

Relative contributions of smooth and striated muscles to the canine urethral pressure profile

Oct 1, 1976·British Journal of Urology·S A Awad, J W Downie

Phenoxybenzamine in the management of neurogenic vesical dysfunction

Dec 1, 1976·The Journal of Urology·D F Mobley

Sympathetic activity in the proximal urethra in patients with urinary obstruction

May 1, 1976·The Journal of Urology·S A AwadS V Jarzylo

The neuropathic urethra

Nov 23, 1974·Lancet·B J AbelK R Krishnan

Analyses of the urethral pressure profile by means of electromyography and the administration of drugs

Apr 1, 1972·British Journal of Urology·P J DonkerE L Noach

Phenoxybenzamine in neurogenic bladder dysfunction. II. Clinical considerations

Dec 1, 1973·The Journal of Urology·R J Krane, C A Olsson

Citations

Autonomic neuropathy, I. Clinical features, investigation, pathophysiology, and treatment

May 1, 1996·Journal of the Neurological Sciences·A J McDougall, J G McLeod

Pharmacologic treatment of stress urinary incontinence: expectations for outcome

Oct 11, 2003·Urology·Bernhard Schuessler, Kaven Baessler

Relative contributions of smooth and striated muscles to the canine urethral pressure profile

Oct 1, 1976·British Journal of Urology·S A Awad, J W Downie

Botulinum toxin A injection to the bladder neck and urethra for medically refractory lower urinary tract symptoms in men without prostatic obstruction

Dec 31, 2009·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Jing-Liang ChenHann-Chorng Kuo

Urethral function in neurological disorders of the lower urinary tract

Sep 1, 1983·Surgical Neurology·W S GunasekeraI D Eversden

Prazosin as cause of urinary incontinence

Dec 1, 1981·Urology·G H KirulutaG M Winsor

The lower urinary tract

Jun 1, 1982·British Journal of Clinical Pharmacology·J M Robinson

Use of internal urethrotomy to reverse upper renal tract dilatation in children with neurogenic bladder dysfunction

Jun 1, 1982·British Journal of Urology·A M Rickwood

Bladder neck incompetence in patients with spinal cord injury: significance of sympathetic skin response

Mar 29, 2000·The Journal of Urology·B RodicB Schurch

Pharmacologic management of urinary incontinence in women

Dec 13, 2002·The Urologic Clinics of North America·Alan J Wein, Eric S Rovner

From intermittent catheterisation to catheter freedom via urodynamics: a tribute to Sir Ludwig Guttmann

May 1, 1979·Paraplegia·A B Rossier, B A Fam

Correlation between lower urinary tract symptoms and urethral function in benign prostatic hyperplasia

Sep 24, 2004·Neurourology and Urodynamics·Hideo NakaiTsuneki Suzuki

Prazosin treatment of neurological patients with detrusor hyperreflexia and bladder emptying disability

Jan 1, 1989·Scandinavian Journal of Urology and Nephrology·T PetersenP Sidenius

Experimental evidence for a central nervous system site of action in the effect of alpha-adrenergic blockers on the external urinary sphincter

Aug 1, 1984·The Journal of Urology·J GajewskiS A Awad

Urethral function after chronic cauda equina lesion in cats. II. The role of autonomically-innervated smooth and striated muscle in distal sphincter dysfunction

Oct 1, 1990·The Journal of Urology·H D FloodS A Awad

Present urological treatment of spinal cord injury patients

Jul 1, 1981·The Journal of Urology·S D Graham

Detrusor bladder neck dyssynergia revisited

Dec 1, 1994·The Journal of Urology·B SchurchA B Rossier

Related Concepts

Adrenergic alpha-Antagonists
Bladder Neck Obstruction
Nervous System Disorder
Phenoxybenzamine Hydrochloride
Z-Max
Sympathetic Nervous System
Urethral Obstruction

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