Alpha-fetoprotein and liver cell proliferation in rats fed choline-deficient diet

Zeitschrift für Ernährungswissenschaft
J H BossG Zajicek

Abstract

Liver 3H-thymidine labelling index and serum AFP were determined in rats fed a standard laboratory or choline deficient diet. A significant increase in the rate of liver cell proliferation was evidenced in animals on the deficient diet. Furthermore, elevated serum AFP levels were detected in a proportion of these rats. It is suggested that increased synthesis of AFP corresponds to liver cell regeneration secondary to hepatic damage.

References

Mar 1, 1975·The American Journal of Physiology·E RosenmannJ H Boss
Jan 21, 1972·Nature·P Alexander
May 15, 1974·Experientia·E RosenmannJ H Boss
Nov 2, 1974·Lancet·A E LeekT Chard
Jul 15, 1971·International Journal of Cancer. Journal International Du Cancer·B de Néchaud, J Uriel
Jul 1, 1948·The Journal of Experimental Medicine·E C MILLER, J A MILLER
Jul 1, 1967·Bulletin of Environmental Contamination and Toxicology·T E Archer, D G Crosby

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