PMID: 7086434Aug 1, 1982Paper

Alpha gamma-enolase in the rat: ontogeny and tissue distribution

Journal of Neurochemistry
O S Jørgensen, G Centervall

Abstract

The rat brain enolases are dimers composed of alpha and gamma subunits. At pH 8.6 alpha gamma-enolase seemed to be stable, and no evidence was found for the possible formation of alpha gamma-enolase from alpha alpha-enolase and gamma gamma-enolase in the course of rat brain homogenization. During ontogeny of the rat forebrain, alpha gamma-enolase was formed before gamma gamma-enolase. The half-maximal specific concentrations were reached at postnatal days 14 and 23, respectively. The distribution of alpha gamma- and gamma gamma-enolase in various rat brain areas was also investigated. In all areas both forms were present. In neuroendocrine tissues alpha gamma-enolase was present at much higher concentration than gamma gamma-enolase. The ratio between gamma gamma-enolase and alpha gamma-enolase may be indicative of the degree of neuronal maturation, a conclusion further substantiated by the high ratio observed in cerebellum and the low ratio observed in olfactory bulbs, both compared with the ratio in forebrain.

References

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Citations

Jul 31, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·E KaiserW Worofka
Apr 1, 1989·Brain Research. Developmental Brain Research·K M HamreJ R West
Jan 1, 1986·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·O S Jørgensen, P Honegger
Jun 1, 1994·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·O S Jørgensen
Jan 1, 1986·Annals of the New York Academy of Sciences·T G Bolwig, O S Jørgensen

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