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Alpha-naphthyl-isothiocyanate-induced cholestasis in the rat: studies of liver plasma membrane enzymes

Pathology

Jan 1, 1975

P J HertzogR N Le Page

PMID: 124851

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Abstract

Oral administration of a single dose of alpha-naphthyl-isothiocyanate (ANIT) to rats produced a conjugated hyperbilirubinaemia, maximal at 2 days and which subsided by 7. The activities of 3 liver plasma membrane enzymes, Mg-2+-ATPase, (Na-+-K-+)-ATPase and 5-nucleotidase, and serum bil...read more

Mentioned in this Paper

Potassium
Bilirubin, (4E,15E)-Isomer
Plasma Membrane
Sodium
DNA-dependent ATPase
Naphthalenes
Electron Microscopy
Cholestasis
Nucleotidases
Thiocyanates
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Alpha-naphthyl-isothiocyanate-induced cholestasis in the rat: studies of liver plasma membrane enzymes

Pathology

Jan 1, 1975

P J HertzogR N Le Page

PMID: 124851

DOI:

Abstract

Oral administration of a single dose of alpha-naphthyl-isothiocyanate (ANIT) to rats produced a conjugated hyperbilirubinaemia, maximal at 2 days and which subsided by 7. The activities of 3 liver plasma membrane enzymes, Mg-2+-ATPase, (Na-+-K-+)-ATPase and 5-nucleotidase, and serum bil...read more

Mentioned in this Paper

Potassium
Bilirubin, (4E,15E)-Isomer
Plasma Membrane
Sodium
DNA-dependent ATPase

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