Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana

BioRxiv : the Preprint Server for Biology
R Axel W WibergM. Kankare


Detecting signatures of ecological adaptation in comparative genomics is challenging, but analysing population samples with characterised geographic distributions, such as clinal variation, can help identify genes showing covariation with important ecological variation. Here we analysed patterns of geographic variation in the cold-adapted species Drosophila montana across phenotypes, genotypes and environmental conditions and searched for signatures of cold adaptation in populations' genomic divergence. We first derived the climatic variables associated with the geographic distribution of 24 populations across two continents to trace the whole scale of environmental variation experienced by the species, and measure variation in the cold tolerance of the flies of six populations from different geographic contexts. We then performed pooled whole genome sequencing of these six populations, and used Bayesian methods to identify SNPs where genetic differentiation is associated with both climatic variables and the population phenotypic measurements. The top candidate SNPs were enriched on the X and 4th chromosomes, and they also lie near genes implicated in other studies of cold tolerance and population divergence in this species and...Continue Reading

Related Concepts

Memory, Short-Term
Positioning Attribute
Spatial Distribution
Alert brand of caffeine
Structure of Cortex of Kidney
Impaired Cognition

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Cell Aging (Preprints)

This feed focuses on cellular aging with emphasis on the mitochondria, autophagy, and metabolic processes associated with aging and longevity. Here is the latest research on cell aging.

Related Papers

Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
Amanda L GilchristPaul Verhaeghen
Proceedings of the National Academy of Sciences of the United States of America
Irene E NagelHauke R Heekeren
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Bradley VoytekAdam Gazzaley
© 2020 Meta ULC. All rights reserved