Altenuene derivatives from an unidentified freshwater fungus in the family Tubeufiaceae.

Journal of Natural Products
Ping JiaoC A Shearer

Abstract

Four new altenuene derivatives called dihydroaltenuenes A (1) and B (2) and dehydroaltenuenes A (3) and B (4), along with five known compounds, including isoaltenuene (5), altenuene (6), and 5'-epialtenuene (7), were isolated from cultures of an unidentified freshwater aquatic fungal species in the family Tubeufiaceae. The structures of 1-4 were determined by analysis of NMR and MS data. The relative stereochemistry was determined on the basis of (1)H NMR J-values and NOE data, while the absolute configuration of a representative member of the group (5) was assigned by CD spectral analysis of its bis-N,N-dimethylaminobenzoate derivative. Compounds 1, 3, 4, 5, and 6 showed antibiotic activity against Gram-positive bacteria.

References

Dec 1, 1984·Journal of Food Protection·John E Schade, A Douglas King

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Citations

Apr 25, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Ziling MaoLigang Zhou
Sep 28, 2014·Fitoterapia·Ying WangLing-Yi Kong
May 27, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Vanessa Mara ChaplaAngela Regina Araújo
Jan 30, 2010·Natural Product Reports·John W BluntMichèle R Prinsep
Mar 17, 2012·Angewandte Chemie·Christian M Gampe, Erick M Carreira
Dec 11, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Changyeol LeeSang Hee Shim
Jan 5, 2021·Russian Journal of Bioorganic Chemistry·A A BaranovaA P Tyurin
Aug 5, 2008·Organic Letters·Darunee SoorukramAnthony G M Barrett
Jun 19, 2009·Chemical Reviews·Stefan BräseCarl F Nising
Jul 4, 2009·Journal of Natural Products·Martina Altemöller, Joachim Podlech
Jul 16, 2013·Organic Letters·Juan Mangas-SánchezVicente Gotor-Fernández

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