PMID: 5257009Mar 1, 1969Paper

Alteration in microsomal protein synthesis during early development of mouse brain

Proceedings of the National Academy of Sciences of the United States of America
T C Johnson, G Belytschko

Abstract

The loss of protein synthesis during early mouse-brain development was shown to be the result, at least in part, of the inability of microsomes obtained from more mature neural tissue to participate in rapid polypeptide synthesis. The loss of brain microsomal activity was observed shortly after birth and continued until the animals were approximately ten days old. Despite the difference in synthetic activity, sucrose gradient profiles of microsomes and polyribosomes from young and more mature brain tissue were quite similar. The loss in protein synthesis was shown to be independent of available mRNA and not attributable to aminoacyl-RNA synthetases and tRNA binding activity.

References

Oct 1, 1968·Journal of Neurochemistry·T C Johnson
Jul 1, 1966·Journal of Neurochemistry·T C Johnson, M W Luttges
Aug 1, 1966·Journal of Molecular Biology·C E ZomzelyC Provost
Apr 1, 1967·Biochemistry·A T Campagnoni, H R Mahler
Nov 1, 1967·Journal of Neurochemistry·T C Johnson
Apr 15, 1957·Experientia·A LAJTHAH WAELSCH
Aug 1, 1957·Experimental Cell Research·T HULTIN, A VON DER DECKEN

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Citations

Apr 1, 1980·Neurochemical Research·J L FandoC G Wasterlain
Mar 1, 1982·Mechanisms of Ageing and Development·S K KimS S Han
Aug 1, 1984·Mechanisms of Ageing and Development·R Vargas, M Castañeda
Jan 1, 1980·Experimental Gerontology·S K KimD J Wagner
Apr 1, 1970·Cell and Tissue Kinetics·E FrindelP Brigham
Aug 1, 1983·Biological Reviews of the Cambridge Philosophical Society·S C Makrides
Aug 1, 1971·Journal of Neurochemistry·D E Johnson, O Z Sellinger
Aug 1, 1971·Journal of Neurochemistry·M P LernerB R Fridlender
Dec 1, 1971·Journal of Neurochemistry·L ChouT C Johnson
Jan 1, 1974·Journal of Neurochemistry·T Yanagihara
Jul 1, 1978·Journal of Neurochemistry·B E Gilbert
Mar 1, 1977·Journal of Neurochemistry·A T Campagnoni, J R Harris
May 1, 1979·Journal of Neurochemistry·P T van der Saag, T F de Greeff
Oct 1, 1974·Journal of Neurochemistry·B E Gilbert, T C Johnson
Nov 1, 1978·Journal of Neurochemistry·K MorimotoT Yanagihara
Mar 1, 1976·Archives of Biochemistry and Biophysics·D K LaymanA Richardson
Jan 1, 1983·Archives of Oral Biology·S K Kim, D W Calkins
Sep 1, 1981·Journal of Neurochemistry·R Vargas, M Castañeda
Feb 9, 1979·Brain Research·E J Metter, T Yanagihara
Jan 1, 1981·Stroke; a Journal of Cerebral Circulation·K Morimoto, T Yanagihara
Jul 1, 1976·Journal of Neurochemistry·T C Johnson

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