PMID: 9537046Jan 1, 1980Paper

Alteration of T-lymphocyte subpopulations in patients with primary renal diseases and systemic lupus erythematosus

Scandinavian Journal of Immunology
K MatsumotoM Hatano

Abstract

Forty-eight patients with a variety of primary renal diseases and systemic lupus erythematosus (SLE) were examined for the proportion of circulating T lymphocytes bearing receptors for IgM (T mu cells) or IgG (T gamma cells). Although the control group showed strikingly similar mean values for both T mu and T gamma cells, the whole group of patients with primary renal diseases and SLE showed a wide scatter of values. Sixteen patients with primary renal diseases and SLE had higher proportions of T gamma cells than the control group, whereas seven patients with chronic glomerulonephritis (CGN), membranoproliferative glomerulonephritis (MPGN), lipoid nephrosis (LN), and SLE showed very marked decrease in the proportions of T gamma cells in the peripheral blood. On the other hand, six out of the total group of patients had low proportions of T mu cells in the peripheral blood. However, no consistent relationship between the proportion of T mu and T gamma cells was found in our study. These findings indicate that there exists a heterogeneity of T-lymphocyte subpopulation distribution in some patients with primary renal diseases and SLE. The possible significance of these phenomena in the pathophysiology of renal diseases is discussed.

References

Oct 1, 1977·European Journal of Immunology·L MorettaM D Cooper
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Jan 1, 1978·Scandinavian Journal of Immunology·S RomagnaniM Ricci
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Citations

Dec 1, 1980·Journal of Reproductive Immunology·S MathurH H Fudenberg
Sep 1, 1983·Kidney International·E G Neilson, B Zakheim
May 1, 1981·Medical Hypotheses·B Daunter, E V Mackay
Oct 22, 2011·Journal of Immunotoxicology·M HorváthováI Hertz-Picciotto
Aug 1, 1981·Scandinavian Journal of Immunology·K Osakabe, K Matsumoto
Jan 1, 1984·Acta Academiae Medicinae Wuhan = Wu-han I Hsüeh Yüan Hsüeh Pao·X ZhouM T Song
Jan 1, 1984·Transactions of the Royal Society of Tropical Medicine and Hygiene·C De SimoneF Sorice

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