Alteration of the left ventricular diastolic pressure-segment length relation produced by the pericardium. Effects of cardiac distension and afterload reduction in conscious dogs

K ShiratoJ Ross


Left ventricular pressure and segment length were measured in seven conscious chronically instrumented dogs with the pericardium intact and 3-9 days after pericardiectomy. Diastolic pressure-length plots were obtained under control conditions and after acute volume loading followed by sodium nitroprusside infusion. In all dogs with intact pericardium, volume loading displaced the entire diastolic pressure-length curve upwards and sodium nitroprusside shifted it toward control. After pericardiectomy the pressure-segment length data during control, volume loading and sodium nitroprusside fell on a single curve (intercepts and slopes not statistically different); After dextran infusion, intrapericardial pressure rose from control 1.5 +/- 0.7 mm Hg to 8.2 +/- 0.5 mm Hg, and it fell to 4.8 +/- 0.1 mm Hg after nitroprusside. Therefore, in acute cardiac dilatation the pericardium contributed significantly to the increased left ventricular diastolic pressure and to the fall during sodium nitroprusside infusion and appeared responsible for shifts in the diastolic pressure-segment length relation.


Jul 1, 1968·Cardiovascular Research·S H BartleJ M Costenbader
Jul 1, 1961·The American Journal of Physiology·L L HEFNERT J REEVES
Nov 1, 1960·Circulation Research·J P HOLTH KINES
Jun 1, 1931·The Journal of Clinical Investigation·J H Gibbon, E D Churchill
Oct 11, 1915·The Journal of Physiology·Y Kuno

❮ Previous
Next ❯


Jan 1, 1987·Annals of Biomedical Engineering·R Beyar, Y Goldstein
Nov 1, 1988·Journal of the American College of Cardiology·S J LavineS J Gunther
Jul 1, 1989·Journal of the American College of Cardiology·J A RumbergerM L Marcus
Apr 1, 1991·Journal of the American College of Cardiology·T TakahashiW Grossman
Nov 1, 1992·Journal of the American College of Cardiology·W HayashidaC Kawai
May 1, 1993·Journal of the American College of Cardiology·O N KrogmannM Bourgeois
Feb 26, 2005·Journal of Cardiac Failure·Ralph Shabetai
Apr 10, 1999·The Annals of Thoracic Surgery·V RaoT E David
Sep 13, 2003·Resuscitation·Michael Frenneaux
Jan 1, 1983·Journal of the American College of Cardiology·J Ross
Nov 1, 1984·Journal of the American College of Cardiology·A KimchiG H Murata
Apr 1, 1984·Journal of the American College of Cardiology·O A SmisethJ V Tyberg
Aug 1, 1985·Journal of the American College of Cardiology·D T ManganoR J Ellis
Dec 1, 1986·Journal of the American College of Cardiology·C M BoltwoodP M Shah
Dec 1, 1987·Journal of the American College of Cardiology·F PiscioneP W Serruys
Jul 1, 2006·Nature Clinical Practice. Cardiovascular Medicine·Lynne Williams, Michael Frenneaux
Sep 1, 1983·Annals of Surgery·M J HoffmanJ L Tatum
Feb 15, 2001·Echocardiography·Ary Ribeiro
Jun 13, 2009·American Journal of Physiology. Gastrointestinal and Liver Physiology·Yanfen JiangRavinder K Mittal
Jun 24, 2004·The Tohoku Journal of Experimental Medicine·Yoshito YamamotoKunio Shirato
Jul 20, 2002·Anesthesiology·Stefan G De HertInez E Rodrigus
Jan 1, 1991·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·S NakataniY Nimura
May 3, 2012·Cardiology Clinics·Louis J Dell'Italia
Aug 1, 1984·Current Problems in Cardiology·C M Boltwood, P M Shah
Dec 15, 1990·The American Journal of Cardiology·P S ReddyB F Uretsky
Sep 1, 1979·Progress in Cardiovascular Diseases·R ShabetaiC B Higgins
Oct 1, 1991·Current Problems in Cardiology·L J Dell'Italia
Jan 1, 1989·Journal of Biomechanics·P N ShivakumarS W Rabkin
Dec 1, 1978·The American Journal of Cardiology·R Shabetai
Dec 15, 2005·Heart, Lung & Circulation·Nitin GhorpadeMorteza Mohajeri
Jan 12, 2001·Current Problems in Cardiology·M A Schmidt, M R Starling
Dec 1, 1983·American Heart Journal·O M HessR Shabetai

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.