PMID: 9434701Jan 22, 1998Paper

Alteration of the neonatal pulmonary physiology after total cardiopulmonary bypass

The Journal of Thoracic and Cardiovascular Surgery
A SerrafC Planché

Abstract

The purpose of this study was to analyze the mechanisms associated with lung injury after cardiopulmonary bypass and to propose strategies of prevention. Thirty-two neonatal piglets underwent 90 minutes of hypothermic cardiopulmonary bypass without aortic cross-clamping. Five experimental groups were defined: group I had standard cardiopulmonary bypass (control), group II received continuous low-flow lung perfusion during cardiopulmonary bypass, group III treatment was similar to that of group I with maintenance of ventilation, group IV received pneumoplegia, and group V received nitric oxide ventilation (30 ppm) after cardiopulmonary bypass. Data drawn from hemodynamic and gas exchange values and muscular and pulmonary tissular levels of adenosine triphosphate (in micromoles per gram) and myeloperoxidase (in international units per 100 mg) were used for comparisons before and 30 and 60 minutes after cardiopulmonary bypass. Pulmonary and systemic vascular endothelial functions were assessed in vitro after cardiopulmonary bypass on isolated rings of pulmonary and iliac arteries. Pulmonary vascular resistance index, cardiac index, and oxygen tension were better preserved in groups II, IV, and V. All groups disclosed a significant...Continue Reading

References

Dec 1, 1993·The Annals of Thoracic Surgery·M J Elliott, A H Finn
Nov 1, 1995·The Annals of Thoracic Surgery·M J EppingerG M Deeb
Jun 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·P M KirshbomJ W Gaynor
Jun 1, 1996·The Annals of Thoracic Surgery·K MoritaL J Ignarro

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Citations

Mar 29, 2000·The Annals of Thoracic Surgery·T SuzukiI Kashima
Sep 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Luca Salvatore De SantoMaurizio Cotrufo
Apr 13, 2001·Acta Anaesthesiologica Scandinavica·M AngdinR Astudillo
Jul 26, 2002·Acta Anaesthesiologica Scandinavica·M Glavind-KristensenV E Hjortdal
Apr 15, 2004·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Niranjan Kissoon
Dec 31, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Jodie Y DuffyJeffrey M Pearl
Feb 28, 2004·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Christopher L HubbleReese H Clark
Feb 2, 1999·American Journal of Respiratory and Critical Care Medicine·A SerrafC Planche
Oct 13, 2000·American Journal of Respiratory and Critical Care Medicine·E FadelP Herve
Jan 13, 2010·Journal of Cardiothoracic Surgery·Efstratios E ApostolakisGeorgios S Papadopoulos
Sep 13, 2008·Interactive Cardiovascular and Thoracic Surgery·Edmo Atique GabrielEnio Buffolo
Jun 25, 2009·Journal of Cardiac Surgery·Efstratios ApostolakisDimitris Dougenis
Apr 24, 1999·The Annals of Thoracic Surgery·P J ChaiR M Ungerleider
Feb 1, 2014·Interactive Cardiovascular and Thoracic Surgery·Erica de Freitas AmorimWalter Villela de Andrade Vicente
Jun 11, 2015·Best Practice & Research. Clinical Anaesthesiology·Julie L Huffmyer, Danja S Groves
Feb 24, 2015·Critical Care Research and Practice·Rafael BadenesF Javier Belda
May 29, 2003·The Journal of Thoracic and Cardiovascular Surgery·Alain SerrafClaude Planché
Apr 12, 2002·Chest·Calvin S H NgAhmed A Arifi
Sep 4, 2009·The Journal of Surgical Research·Jeffrey M PearlJodie Y Duffy
Dec 19, 2003·Asian Cardiovascular & Thoracic Annals·Zhao Kang SuZhi Wei Xu
Nov 6, 2008·Asian Cardiovascular & Thoracic Annals·Enisa M F CarvalhoTomas A Salerno
Aug 14, 2020·Journal of Cardiac Surgery·Mehmet KaracalilarMehmet Yeniterzi
Oct 22, 2009·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Calvin S H NgMalcolm J Underwood
Sep 27, 2001·Endothelium : Journal of Endothelial Cell Research·C E Patterson, H Lum
May 30, 2006·The Annals of Thoracic Surgery·Deborah J Kozik, James S Tweddell

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