Alterations in amino acid concentrations in the plasma and muscle in human subjects during 24 h of simulated adventure racing.

European Journal of Applied Physiology
Marcus BorgenvikB Ekblom

Abstract

This investigation was designed to evaluate changes in plasma and muscle levels of free amino acids during an ultra-endurance exercise and following recovery. Nine male ultra-endurance trained athletes participated in a 24-h standardized endurance trial with controlled energy intake. The participants performed 12 sessions of running, kayaking and cycling (4 × each discipline). Blood samples were collected before, during and after exercise, as well as after 28 h of recovery. Muscle biopsies were taken before the test and after exercise, as well as after 28 h of recovery. During the 24-h exercise, plasma levels of branched-chain (BCAA), essential amino acids (EAA) and glutamine fell 13, 14 and 19% (P < 0.05), respectively, whereas their concentrations in muscle were unaltered. Simultaneously, tyrosine and phenylalanine levels rose 38 and 50% (P < 0.05) in the plasma and 66 and 46% (P < 0.05) in muscle, respectively. After the 24-h exercise, plasma levels of BCAA were positively correlated with muscle levels of glycogen (r (2) = 0.73, P < 0.05), as was the combined concentrations of muscle tyrosine and phenylalanine with plasma creatine kinase (R (2) = 0.55, P < 0.05). Following 28-h of recovery, plasma and muscle levels of amino ...Continue Reading

References

Apr 12, 1979·European Journal of Applied Physiology and Occupational Physiology·J DécombazJ R Poortmans
Dec 6, 1976·European Journal of Applied Physiology and Occupational Physiology·G Haralambie, A Berg
Dec 1, 1992·Medicine and Science in Sports and Exercise·M Parry-BillingsE A Newsholme
Jul 31, 1986·Biochemical and Biophysical Research Communications·D Danieli BettoR Betto
Aug 1, 1974·Journal of Applied Physiology·D B Dill, D L Costill
Nov 1, 1981·Clinical Science·M J RennieD J Millward
Feb 1, 1995·Journal of Applied Physiology·T E GrahamE A Richter
Jan 1, 1993·The Japanese Journal of Physiology·F HuqP Ruell
Dec 1, 1995·Medicine and Science in Sports and Exercise·P Dempster, S Aitkens
Feb 1, 1996·International Journal of Sports Medicine·K Nosaka, P M Clarkson
Apr 30, 1998·British Journal of Sports Medicine·K J KingsburyM Hjelm
Jul 7, 2000·Muscle & Nerve·J L Andersen, P Aagaard
Mar 20, 2001·International Journal of Sport Nutrition and Exercise Metabolism·M H Hargreaves, R Snow
May 29, 2004·American Journal of Physiology. Endocrinology and Metabolism·René KoopmanAnton J M Wagenmakers
Jun 24, 2004·Nutrition·Mark Tarnopolsky
Sep 25, 2007·Sports Medicine·Jason C TeeMike I Lambert
Jun 3, 2009·Scandinavian Journal of Medicine & Science in Sports·C M MattssonB Ekblom
May 22, 2010·Journal of Applied Physiology·Krista R HowarthMartin J Gibala
Jun 15, 2010·Journal of Sports Sciences·Jonas K EnqvistBjörn T Ekblom

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medicine and Science in Sports and Exercise
Linda Suzan Lamont
Metabolism: Clinical and Experimental
G Haralambie, M Mössinger
European Journal of Applied Physiology and Occupational Physiology
J R CadeM J Fregly
© 2022 Meta ULC. All rights reserved