Alterations in creatinine clearance during respiratory distress syndrome

Biology of the Neonate
T TulassayB Büky


Some renal parameters have been studied in newborns with respiratory distress syndrome (RDS). During the first 24 h, the serum creatinine level of the severe cases of RDS are significantly increased, decreasing gradually with improvement of the RDS and reaching normal values within 10 days. Blood urea nitrogen remained unchanged. In the milder cases of RDS, the serum creatinine also showed a slighter increase, which became normal within 4 days after birth. During the acute phase of RDS, there is a reversible impairment in the renal function, which correlates with the degree of hypoxia, hypercapnia and acidosis determined by the primary disease.


Oct 1, 1988·European Journal of Pediatrics·A J van der HeijdenP J Sauer
Oct 1, 1992·Archives of Disease in Childhood·B H Wilkins
Aug 17, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·M G Coulthard, E N Hey
Oct 1, 1993·Early Human Development·J Simpson, T Stephenson
May 17, 2003·European Journal of Pediatrics·Vasilios I GiaprosStyliani K Andronikou

Related Concepts

Blood Urea Nitrogen Measurement
Hydrogen-Ion Concentration
Kidney Function Tests
Respiratory Distress Syndrome, Newborn

Related Feeds


Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.