Measures assessing resting-state brain activity with blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) can reveal cognitive disorders at an early stage. Analysis of regional homogeneity (ReHo) measures the local synchronization of spontaneous fMRI signals and has been successfully utilized in detecting alterations in subjects with attention-deficit hyperactivity disorder (ADHD), depression, schizophrenia, Parkinson's disease and Alzheimer's dementia. Resting-state brain activity was investigated in 28 adolescents with autism spectrum disorders (ASD) and 27 typically developing controls being imaged with BOLD fMRI and analyzed with the ReHo method. The hypothesis was that ReHo of resting-state brain activity would be different between ASD subjects and controls in brain areas previously shown to display functional alterations in stimulus or task based fMRI studies. Compared with the controls, the subjects with ASD had significantly decreased ReHo in right superior temporal sulcus region, right inferior and middle frontal gyri, bilateral cerebellar crus I, right insula and right postcentral gyrus. Significantly increased ReHo was discovered in right thalamus, left inferior frontal and anterior subcal...Continue Reading
Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data
Functional connectivity in single and multislice echoplanar imaging using resting-state fluctuations
Differential effects of developmental cerebellar abnormality on cognitive and motor functions in the cerebellum: an fMRI study of autism
Abnormal variability and distribution of functional maps in autism: an FMRI study of visuomotor learning
Why the frontal cortex in autism might be talking only to itself: local over-connectivity but long-distance disconnection
Similarities in the phenotype of the auditory neural substrate in children with Asperger syndrome and their parents
Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders
Decreased regional homogeneity in schizophrenia: a resting state functional magnetic resonance imaging study
Frequency of epileptiform EEG abnormalities in a sequential screening of autistic patients with no known clinical epilepsy from 1996 to 2005
Abnormal neural activity in children with attention deficit hyperactivity disorder: a resting-state functional magnetic resonance imaging study
Inhibitory control in high-functioning autism: decreased activation and underconnectivity in inhibition networks
Regional coherence changes in the early stages of Alzheimer's disease: a combined structural and resting-state functional MRI study
An epidemiological and diagnostic study of Asperger syndrome according to four sets of diagnostic criteria
The superior temporal sulcus performs a common function for social and speech perception: implications for the emergence of autism
Neural correlates of simple unimanual discrete and continuous movements: a functional imaging study at 3 T
Fisher discriminative analysis of resting-state brain function for attention-deficit/hyperactivity disorder
Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: a review of resting-state fMRI studies
Abnormal neural activity in the patients with remitted geriatric depression: a resting-state functional magnetic resonance imaging study
A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks.
Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysis
Regional homogeneity in depression and its relationship with separate depressive symptom clusters: a resting-state fMRI study
When does the Autism Spectrum Screening Questionnaire (ASSQ) predict autism spectrum disorders in primary school-aged children?
Functional reorganization associated with outcome in hand function after stroke revealed by regional homogeneity
Valence scaling of dynamic facial expressions is altered in high-functioning subjects with autism spectrum disorders: an fMRI study
Autism spectrum disorder: does neuroimaging support the DSM-5 proposal for a symptom dyad? A systematic review of functional magnetic resonance imaging and diffusion tensor imaging studies.
Eyes-open/eyes-closed dataset sharing for reproducibility evaluation of resting state fMRI data analysis methods
Altered regional homogeneity in post-traumatic stress disorder: a resting-state functional magnetic resonance imaging study.
A resting-state connectivity metric independent of temporal signal-to-noise ratio and signal amplitude
Evidence for association between Disrupted-in-Schizophrenia 1 (DISC1) gene polymorphisms and autism in Chinese Han population: a family-based association study.
5-HTTLPR polymorphism impacts task-evoked and resting-state activities of the amygdala in Han Chinese.
Regional homogeneity within the default mode network in bipolar depression: a resting-state functional magnetic resonance imaging study
Alterations in regional homogeneity of spontaneous brain activity in late-life subthreshold depression
Abnormal Spontaneous Neural Activity in Obsessive-Compulsive Disorder: A Resting-State Functional Magnetic Resonance Imaging Study
Altered pattern of spontaneous brain activity in the patients with end-stage renal disease: a resting-state functional MRI study with regional homogeneity analysis
Identify changes of brain regional homogeneity in bipolar disorder and unipolar depression using resting-state FMRI
Altered spontaneous brain activity in patients with Parkinson's disease accompanied by depressive symptoms, as revealed by regional homogeneity and functional connectivity in the prefrontal-limbic system
Exploring the patterns of acupuncture on mild cognitive impairment patients using regional homogeneity
The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism
Different neural manifestations of two slow frequency bands in resting functional magnetic resonance imaging: a systemic survey at regional, interregional, and network levels
Graph theoretical analysis reveals the reorganization of the brain network pattern in primary open angle glaucoma patients
Local brain connectivity across development in autism spectrum disorder: A cross-sectional investigation
Linking neocortical, cognitive, and genetic variability in autism with alterations of brain plasticity: the Trigger-Threshold-Target model
Altered functional connectivity of the amygdaloid input nuclei in adolescents and young adults with autism spectrum disorder: a resting state fMRI study
Three-Dimensional Eigenbrain for the Detection of Subjects and Brain Regions Related with Alzheimer's Disease
Connectivity disruptions in resting-state functional brain networks in children with temporal lobe epilepsy
Altered Local Spontaneous Brain Activity in Juvenile Myoclonic Epilepsy: A Preliminary Resting-State fMRI Study
Alteration of brain regional homogeneity of monkeys with spinal cord injury: A longitudinal resting-state functional magnetic resonance imaging study
Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.
Alzheimer's Disease: Neuroimaging
Neuroimaging can help identify pathological hallmarks of Alzheimer's disease (AD). Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.
Autism spectrum disorder is associated with challenges with social skills, repetitive behaviors, and often accompanied by sensory sensitivities and medical issues. Here is the latest research on autism.