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Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome

Cold Spring Harbor Symposia on Quantitative Biology

Apr 19, 2017

Joanna Achinger-KaweckaSusan J Clark

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Abstract

The structural and functional basis of the genome is provided by the three-dimensional (3D) chromatin state. To enable accurate gene regulation, enhancer elements and promoter regions are brought into close spatial proximity to ensure proper, cell type-specific gene expression. In cance...read more

Mentioned in this Paper

Gene Expression
Antineoplastic Agents
Study of Epigenetics
Proximal
Tumor Cells, Malignant
Chromatin
Three-dimensional
Enhancer Elements, Genetic
Genome
Metazoa
9
42
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  • Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome

    Cold Spring Harbor Symposia on Quantitative Biology

    Apr 19, 2017

    Joanna Achinger-KaweckaSusan J Clark

    PMID: 28424341

    DOI: 10.1101/sqb.2016.81.031013

    Abstract

    The structural and functional basis of the genome is provided by the three-dimensional (3D) chromatin state. To enable accurate gene regulation, enhancer elements and promoter regions are brought into close spatial proximity to ensure proper, cell type-specific gene expression. In cance...read more

    Mentioned in this Paper

    Gene Expression
    Antineoplastic Agents
    Study of Epigenetics
    Proximal
    Tumor Cells, Malignant
    9
    42

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