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Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome

Cold Spring Harbor Symposia on Quantitative Biology

Apr 21, 2017

Joanna Achinger-KaweckaSusan J Clark

Abstract

The structural and functional basis of the genome is provided by the three-dimensional (3D) chromatin state. To enable accurate gene regulation, enhancer elements and promoter regions are brought into close spatial proximity to ensure proper, cell type-specific gene expression. In cance...read more

Mentioned in this Paper

Proximal
Epigenetic Process
Sequencing
Study of Epigenetics
beta-methylene thiazole-4-carboxamide adenine dinucleotide
Antineoplastic Agents
Promoter Regions, Genetic
Prostatic Neoplasms
Tumor Cells, Malignant
Metazoa
9
43
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Alterations in Three-Dimensional Organization of the Cancer Genome and Epigenome

Cold Spring Harbor Symposia on Quantitative Biology

Apr 21, 2017

Joanna Achinger-KaweckaSusan J Clark

PMID: 28424341

DOI: 10.1101/sqb.2016.81.031013

Abstract

The structural and functional basis of the genome is provided by the three-dimensional (3D) chromatin state. To enable accurate gene regulation, enhancer elements and promoter regions are brought into close spatial proximity to ensure proper, cell type-specific gene expression. In cance...read more

Mentioned in this Paper

Proximal
Epigenetic Process
Sequencing
Study of Epigenetics
beta-methylene thiazole-4-carboxamide adenine dinucleotide
Antineoplastic Agents
Promoter Regions, Genetic
Prostatic Neoplasms
Tumor Cells, Malignant
Metazoa
9
43

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Paper Details
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