Alterations of energy metabolism induced by hexadecane in mice.

Archives internationales de physiologie et de biochimie
J HuguetM Alemany

Abstract

Two groups of young male OF-1 mice were fed for 60 days with cafeteria or, as controls, with standard pellet diet respectively. At that time, both groups were daily treated with hexadecane (HDK) on the skin. HDK induced a drastic body weight loss much higher in cafeteria than control mice. White adipose tissue were exhausted after 4 days of treatment in controls but not after 10 days in cafeteria ones. HDK resulted in mobilization of liver glycogen in both groups while muscle glycogen decreased slightly in the end. Hexadecane treatment did not result in massively enhanced nitrogen metabolism, as the actual oxidation of amino acids decreased considerably as indicated by the low levels of plasma urea. The results could be explained by powerful and lasting effects of hexadecane on thermogenesis and metabolic reserve balance. The use of this material for pharmacological manipulation of body weight appeared difficult.

References

Jan 1, 1977·Annual Review of Biochemistry·E C Lin
Oct 1, 1978·Analytical Biochemistry·V F KalbR W Bernlohr
Aug 1, 1976·The American Journal of Physiology·R K ConleeW W Winder
Sep 1, 1976·Physiology & Behavior·A Sclafani, D Springer
Jan 1, 1986·The British Journal of Nutrition·J SalvadóL Arola
Sep 15, 1985·The Biochemical Journal·T BarberJ Cabo
Apr 1, 1969·Physiological Reviews·R E Smith, B A Horwitz
Jul 1, 1984·Canadian Journal of Biochemistry and Cell Biology = Revue Canadienne De Biochimie Et Biologie Cellulaire·L J Bukowiecki
May 1, 1982·The American Journal of Physiology·K Sato, F Sato
Jan 1, 1962·The Biochemical Journal·D H WILLIAMSONH A KREBS

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Citations

Jan 1, 1993·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A Rodríguez-MartínM Alemany

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