Altered endogenous negativities of the visual event-related potential in remitted schizophrenia

Electroencephalography and Clinical Neurophysiology
H MatsuokaM Sato

Abstract

Visual event-related potentials (ERPs) were recorded during a simple response task (SRT) and a discriminative response task (DRT) in remitted schizophrenic outpatients and age-matched controls to examine 2 endogenous negative potentials: NA and N2c. The NA potentials were derived by subtracting the ERPs for SRT from those for non-target stimuli in DRT. Other subtracting wave forms, N2c potentials, were calculated as the difference between ERPs for target and non-target stimuli in DRT. Schizophrenics showed retardation in NA and N2c peaks and degradation in N2c amplitude relative to controls. The NA peak latency increased as much as the latencies of N2c and reaction time for DRT in schizophrenia. The NA peak emerged prior to the N2c peak, while the NA peak latency correlated closely with the N2c latency. These results indicate that the retarded NA peak latency may serve as a physiological marker for neurobiological vulnerability of schizophrenia.

References

Apr 11, 1990·Electroencephalography and Clinical Neurophysiology·G P NovakM L Wiznitzer
Oct 1, 1991·Electroencephalography and Clinical Neurophysiology·R J StrandburgJ Higa
Nov 15, 1991·Biological Psychiatry·A M ShelleyN McConaghy
Jan 1, 1986·Electroencephalography and Clinical Neurophysiology·D LovrichW Ritter
Apr 1, 1987·Electroencephalography and Clinical Neurophysiology·M BrecherH Begleiter
Mar 1, 1988·Electroencephalography and Clinical Neurophysiology·W RitterH G Vaughan
Jan 1, 1985·Electroencephalography and Clinical Neurophysiology·R SimsonH G Vaughan
Jul 1, 1986·Psychological Bulletin·W S Pritchard
Jan 1, 1987·Schizophrenia Bulletin·P S Holzman
Jan 1, 1986·Schizophrenia Bulletin·D LukoffK H Nuechterlein
Aug 1, 1981·The Journal of Nervous and Mental Disease·J Zubin, S Steinhauer
May 1, 1980·The British Journal of Psychiatry : the Journal of Mental Science·L Ciompi
May 1, 1994·Psychophysiology·R J StrandburgK H Nuechterlein
Oct 1, 1989·Journal of Cognitive Neuroscience·M SchergT W Picton

❮ Previous
Next ❯

Citations

May 28, 2008·European Archives of Psychiatry and Clinical Neuroscience·Sherlyn YeapJohn J Foxe
Dec 28, 1999·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·J KayserJ M Gorman
Oct 17, 2003·Brain Research. Cognitive Brain Research·Minna Valkonen-KorhonenJohannes Lehtonen
Mar 29, 2001·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·K MatsumotoM Sato
Jul 10, 2001·Psychiatry and Clinical Neurosciences·H SaitoM Sato
Sep 14, 2001·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M BrázdilJ Chrastina
Sep 21, 2006·Brain : a Journal of Neurology·Pamela D ButlerDaniel C Javitt
Aug 2, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Isaac SchechterDaniel C Javitt
Dec 31, 2003·Psychophysiology·Yang-Whan Jeon, John Polich
Apr 12, 2005·Brain Research. Cognitive Brain Research·Minna Valkonen-KorhonenJari Karhu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.