Altered gravitational experience during early periods of life affects the static vestibulo-ocular reflex of tadpoles of the southern clawed toad, Xenopus laevis Daudin

Experimental Brain Research
C SebastianE Horn

Abstract

The effects of altered gravitational forces (AGF) on the development of the static vestibulo-ocular reflex (VOR) were investigated in Xenopus laevis tadpoles exposed to hypergravity (1.4g; 3g) or microgravity conditions (German spacelab mission D-2) for 9-10 days. The effects of light conditions during development were also tested by exposing tadpoles to either complete darkness (DD) or 12:12 h light-dark conditions (LD). The static VOR was induced by lateral roll. The efficacy of the VOR circuit after termination of AGF conditions was described by the peak-to-peak amplitude of the sinusoidal VOR characteristics (i.e. amplitude). The static VOR was first observed at stage 41 for both LD and DD tadpoles. Its further development was retarded in the DD tadpoles compared with the LD tadpoles up to stage 48. Microgravity as well as hypergravity exposure caused a significant (P < 0.05, at least) decrease in the static VOR amplitude during the first week after termination of the AGF period. The decreases were 39.4% in the microgravity group, 16.2% in the 1.4g group and 24.9-42.9% in the 3g group compared with the 1g ground-reared siblings at the same developmental stages. The response deficits usually disappeared but persisted for at ...Continue Reading

Citations

Oct 24, 2001·Acta Astronautica·E HornH Agricola
Oct 31, 1998·Brain Research. Brain Research Reviews·A M DupratL Gualandris-Parisot
Jan 22, 2002·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·C Sebastian, E Horn
Jan 17, 2003·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·H Rahmann, R H Anken
Jan 17, 2003·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·E Horn, C Sebastian
Sep 7, 2001·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·R J Wassersug, M Yamashita
Apr 12, 2011·PloS One·Pavel M BalabanRichard Boyle
Aug 26, 2011·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Eberhard R Horn, Martin Gabriel
Jun 6, 2000·Neuron·F M InglisR G Kalb
May 10, 2012·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Martin GabrielEberhard R Horn
May 12, 2009·Cell Biology International·Angela M RizzoBruno Berra
Sep 16, 2003·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·K Slenzka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.