Altered likelihood of brain activation in attention and working memory networks in patients with multiple sclerosis: an ALE meta-analysis

Neuroscience and Biobehavioral Reviews
K KollndorferV Schöpf

Abstract

Multiple sclerosis (MS) is a chronic neurological disease, frequently affecting attention and working memory functions. Functional imaging studies investigating those functions in MS patients are hard to compare, as they include heterogeneous patient groups and use different paradigms for cognitive testing. The aim of this study was to investigate alterations in neuronal activation between MS patients and healthy controls performing attention and working memory tasks. Two meta-analyses of previously published fMRI studies investigating attention and working memory were conducted for MS patients and healthy controls, respectively. Resulting maps were contrasted to compare brain activation in patients and healthy controls. Significantly increased brain activation in the inferior parietal lobule and the dorsolateral prefrontal cortex was detected for healthy controls. In contrast, higher neuronal activation in MS patients was obtained in the left ventrolateral prefrontal cortex and the right premotor area. With this meta-analytic approach previous results of investigations examining cognitive function using fMRI are summarized and compared. Therefore a more general view on cognitive dysfunction in this heterogeneous disease is ena...Continue Reading

References

Jan 1, 1990·Archives of Neurology·J M PeyserE Kaplan
Aug 17, 2001·Journal of Cognitive Neuroscience·C M ArringtonS M Rao
Feb 3, 2005·Psychological Science·John T SerencesSteven Yantis
Mar 19, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·M S A DeloireB Brochet
Apr 13, 2005·Clinical Neurology and Neurosurgery·Guy NagelsPeter Paul De Deyn
May 6, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·J Michelle KincadeMaurizio Corbetta
Dec 6, 2005·Neuroscience·E AwhS-H Oh
Apr 29, 2006·Journal of the Neurological Sciences·Stephan C J HuijbregtsChris H Polman
Jun 22, 2006·Proceedings of the National Academy of Sciences of the United States of America·Michael D FoxMarcus E Raichle
Sep 20, 2006·Journal of the International Neuropsychological Society : JINS·Ralph H B BenedictBianca Weinstock-Guttman
Oct 3, 2006·Brain : a Journal of Neurology·Christiana LeonardGuinevere Eden
Feb 3, 2007·Human Brain Mapping·Jack L LancasterPeter T Fox
Mar 24, 2007·Current Opinion in Neurobiology·Marvin M Chun, Nicholas B Turk-Browne
Jan 23, 2008·Multiple Sclerosis : Clinical and Laboratory Research·K S CardinalN L Sicotte
May 10, 2008·Neuron·Maurizio CorbettaGordon L Shulman
Jul 9, 2008·Neurology·Alvaro Alonso, Miguel A Hernán
Nov 15, 2008·Lancet Neurology·Nancy D Chiaravalloti, John DeLuca
Dec 11, 2008·Neuroimaging Clinics of North America·Hans Lassmann
Apr 10, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gordon L ShulmanMaurizio Corbetta
Jul 20, 2010·Brain : a Journal of Neurology·Amy Deep-SoboslayBrita Elvevåg
Sep 21, 2010·Cerebral Cortex·Gregor KasprianDaniela Prayer
Dec 28, 2010·Neuropsychologia·Adam Gazzaley
Jan 18, 2011·Multiple Sclerosis : Clinical and Laboratory Research·Simona BonavitaGioacchino Tedeschi
Jun 15, 2011·Trends in Cognitive Sciences·Christian N L OliversPieter R Roelfsema
Oct 4, 2011·NeuroImage·Simon B EickhoffPeter T Fox
Jan 27, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xiaotong WenMingzhou Ding
Feb 7, 2012·Multiple Sclerosis : Clinical and Laboratory Research·Anthony FaivreBertrand Audoin
Jul 14, 2012·Current Neurology and Neuroscience Reports·Jesus Lovera, Blake Kovner
Aug 4, 2012·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Miguel E Rentería

❮ Previous
Next ❯

Citations

Oct 10, 2015·Archives of Physical Medicine and Rehabilitation·Jeffrey R HebertThorsten Rudroff
May 31, 2016·Multiple Sclerosis and Related Disorders·M HuiskampN D Chiaravalloti
Jul 22, 2014·Human Brain Mapping·Maria A RoccaUNKNOWN MAGNIMS fMRI Study Group
Aug 19, 2015·Frontiers in Behavioral Neuroscience·Junhai XuShuwei Liu
Jul 3, 2016·Human Movement Science·Matthew B DownerMichelle Ploughman
Oct 22, 2015·Brain Imaging and Behavior·Bei ZhangXiang Wang
Jun 17, 2016·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Olga MarshallYulin Ge
Feb 23, 2017·Neuromodulation : Journal of the International Neuromodulation Society·Leigh CharvetMargaret Kasschau
Jun 30, 2016·Multiple Sclerosis : Clinical and Laboratory Research·Laura VacchiMassimo Filippi
Jul 14, 2018·Multiple Sclerosis : Clinical and Laboratory Research·Fuchun LinMichael G Dwyer
Nov 1, 2018·Brain Imaging and Behavior·Laura BonzanoMarco Bove
May 8, 2018·Child Development·Zachary Yaple, Marie Arsalidou
Jun 11, 2020·Scientific Reports·Alejandra Figueroa-VargasPablo Billeke
Oct 6, 2020·Multiple Sclerosis : Clinical and Laboratory Research·Dániel VerébZsigmond Tamás Kincses

❮ Previous
Next ❯

Software Mentioned

PASAT
GingerALE

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.