Altered mandibular function and prevention of skeletal asymmetries after unilateral condylectomy in rats

European Journal of Orthodontics
M N Spyropoulos, A I Tsolakis

Abstract

Unilateral condylar injury is known to be a frequent cause of mandibular asymmetry. Whether this is due to the trauma itself or to the disturbed function that follows the injury is a very important question with ramifications for clinical complications related to facial asymmetries. The aim of this study was to test the hypothesis that mandibular function in a protruded position can compensate for the absence of one condyle and prevent potential growth asymmetries. Forty-eight 4-week-old rats were divided into two experimental and two control groups consisting of 12 animals each, as follows: (A) unilateral condylectomy was performed on the right side and the mandible was left to function normally; (B) after unilateral condylectomy on the right side, the mandible was forced to function in a protruded position; (C) a sham operation was performed in the condylar area of the right side but no appliance was used; and (D) 12 animals were used as controls without any operation or appliance. Mandibular protraction was achieved by means of a specific appliance, acting via rubber bands, pulling the mandible in a straight, forward direction with a force of 25 g for 12 hours per day. The experimental period was 30 days. Dorsoventral radiog...Continue Reading

Citations

Apr 22, 2015·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Zhengxi ChenGang Shen
Mar 31, 2009·Journal of Dental Research·M NakanoK Tanne
Feb 27, 2013·Journal of Dental Research·T FujitaK Tanne
Mar 26, 2008·The Journal of Craniofacial Surgery·Valerio CervelliFrancesco Mugnaini
Apr 15, 2017·Pediatric Rheumatology Online Journal·Julia von BremenSabine Ruf

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