Altered mechanical interaction between rat plantar flexors due to changes in intermuscular connectivity

Scandinavian Journal of Medicine & Science in Sports
Michel BernabeiHuub Maas

Abstract

Connective tissue formation following muscle injury and remedial surgery may involve changes in the stiffness and configuration of the connective tissues linking adjacent muscles. We investigated changes in mechanical interaction of muscles by implanting either a tissue-integrating mesh (n = 8) or an adhesion barrier (n = 8) to respectively increase or decrease the intermuscular connectivity between soleus muscle (SO) and the lateral gastrocnemius and plantaris complex (LG+PL) of the rat. As a measure of mechanical interaction, changes in SO tendon forces and proximal-distal LG+PL force differences in response to lengthening LG+PL proximally were assessed 1 and 2 weeks post-surgery. The extent of mechanical interaction was doubled 1 week post-implantation of the tissue-integrating mesh compared to an unaffected compartment (n = 8), and was more than four times higher 2 weeks post-surgery. This was found only for maximally activated muscles, but not when passive. Implanting the adhesion barrier did not result in a reduction of the mechanical interaction between these muscles. Our findings indicate that the ratio of force transmitted via myofascial, rather than myotendinous pathways, can increase substantially when the connectivi...Continue Reading

References

Apr 1, 1969·The Journal of Physiology·P G Nelson
Feb 1, 1997·Developmental Medicine and Child Neurology·S A Riewald, S L Delp
Nov 21, 2000·Scandinavian Journal of Medicine & Science in Sports·M KääriäinenH Kalimo
Aug 10, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Mark J C SmeuldersPeter A Huijing
May 1, 1965·The Journal of Physiology·A J BULLER, D M LEWIS
Nov 8, 2003·Skeletal Radiology·Garry E GoldScott L Delp
Mar 27, 2004·Clinical Orthopaedics and Related Research·Mark J C SmeuldersChantal M A M van der Horst
Jun 7, 2005·Muscle & Nerve·Mark J C SmeuldersChantal M A M van der Horst
Mar 21, 2007·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Mark J C Smeulders, Michiel Kreulen
Mar 31, 2007·Journal of Electromyography and Kinesiology : Official Journal of the International Society of Electrophysiological Kinesiology·Can A Yucesoy, Peter A Huijing
Dec 7, 2007·Journal of Biomechanics·Will L JohnsonV Reggie Edgerton
Dec 19, 2008·Medicine and Science in Sports and Exercise·Thomas G Sandercock, Huub Maas
Mar 10, 2009·Neurorehabilitation and Neural Repair·David S K MagnusonDarlene Burke
Apr 28, 2009·British Medical Bulletin·Anil KhannaNicola Maffulli
Apr 17, 2010·Journal of Biomedicine & Biotechnology·Huub Maas, Thomas G Sandercock
May 18, 2010·Journal of Biomechanics·Amy SilderDarryl G Thelen
Oct 5, 2010·Journal of Applied Physiology·Jens Bojsen-MøllerS Peter Magnusson
Feb 22, 2011·The American Journal of Sports Medicine·Jan EkstrandMarkus Waldén
Apr 29, 2011·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Marta RodríguezJuan M Bellón
Jun 1, 2013·Journal of Biomechanical Engineering·Alper YamanCan A Yucesoy

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Citations

May 20, 2016·Biomechanics and Modeling in Mechanobiology·Michel BernabeiJaap H van Dieën
Sep 1, 2017·Exercise and Sport Sciences Reviews·Huub Maas, Taija Finni
Feb 17, 2017·The Journal of Experimental Biology·Michel BernabeiHuub Maas
Jun 7, 2018·Integrative and Comparative Biology·Chris TijsHuub Maas
Apr 3, 2019·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Natalie C Holt
Aug 24, 2018·Integrative and Comparative Biology·C D Williams, N C Holt

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