Abstract
Moral decision-making essentially contributes to social conduct. Although patients with Parkinson's disease (PD) show deficits in (non-moral) decision making and related neuropsychological functions, i.e. executive functions, theory of mind (ToM), and empathy, moral decision-making has rarely been examined in PD patients. We examined possible alterations of moral decision-making and associated functions in PD. Twenty non-demented PD patients and 23 age- and education-matched healthy control participants were examined with tests that assess reasoning, executive functions (set-shifting and planning), ToM and empathy, decision-making under risk, and moral intuitions. Moral decision-making was assessed with a close-to-everyday moral dilemma paradigm that opposes socially oriented "altruistic" choices to self-beneficial "egoistic" choices in 20 moral dilemma short stories (10 high and 10 low emotional). Concurrently, electrodermal activity was recorded. PD patients made more egoistic moral decisions than healthy controls. Remarkably, while reasoning, planning and empathy correlated with moral decision-making in the control group, in the PD group neuropsychological functions and dopaminergic medication did not correlate with moral de...Continue Reading
References
Oct 12, 2004·Neuron·Joshua D GreeneJonathan D Cohen
Aug 15, 2006·Neuroscience and Biobehavioral Reviews·Tania Singer
Aug 21, 2007·Parkinsonism & Related Disorders·Elke KalbeJosef Kessler
Jan 8, 2009·Neuroscience and Biobehavioral Reviews·Jorge Moll, Jay Schulkin
Jun 24, 2009·Neuropsychologia·Frank EuteneuerElke Kalbe
Nov 21, 2009·Journal of Cognitive Neuroscience·Giovanna MorettoGiuseppe di Pellegrino
May 11, 2010·Journal of Neuroscience Methods·Mathias Benedek, Christian Kaernbach
Aug 10, 2010·Psychoneuroendocrinology·Katrin StarckeMatthias Brand
Nov 10, 2010·Social Neuroscience·Manuela FumagalliAlberto Priori
Jan 18, 2011·Behavioural Brain Research·Michele PolettiMauro Adenzato
Jan 20, 2011·Journal of Personality and Social Psychology·Jesse GrahamPeter H Ditto
Jun 8, 2011·Journal of Research in Personality·Eyal AharoniKent A Kiehl
Sep 16, 2011·Personality & Social Psychology Bulletin·Evan Polman, Rachel L Ruttan
Feb 16, 2012·Brain : a Journal of Neurology·Manuela Fumagalli, Alberto Priori
Oct 2, 2012·Annual Review of Psychology·Adele Diamond
Dec 25, 2012·Frontiers in Integrative Neuroscience·Richard PattersonAron K Barbey
Apr 18, 2013·PloS One·Ezequiel Gleichgerrcht, Liane Young
Jun 14, 2013·Frontiers in Human Neuroscience·Sébastien TassyBruno Wicker
Sep 7, 2013·Journal of Neuropsychology·Georg Dirnberger, Marjan Jahanshahi
Sep 18, 2013·Neuropsychology·Jan B RosenElke Kalbe
Jun 28, 2014·Social Neuroscience·Monika SommerBeate Sodian
Citations
May 6, 2016·Frontiers in Behavioral Neuroscience·Jan B RosenElke Kalbe
Aug 29, 2018·Movement Disorders : Official Journal of the Movement Disorder Society·P SantensB R Bloem
Apr 2, 2019·PloS One·Nina SingerBrigitte M Kudielka
Oct 31, 2018·Scientific Reports·Rwei-Ling YuChun-Hsiang Tan
Aug 2, 2017·Journal of Parkinson's Disease·Nele SchmidtKarsten Witt
Dec 12, 2019·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·E A Lyashenko, O V Iakovleva
Jul 18, 2018·Acta neurologica Belgica·Patrick SantensMiet De Letter
Oct 23, 2020·Neuroscience and Biobehavioral Reviews·A M ForanS C Bowden
Feb 10, 2021·Fortschritte der Neurologie-Psychiatrie·Inga Liepelt-ScarfoneSandra Roeske
Feb 27, 2021·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Panpan HuKai Wang
Mar 4, 2021·NPJ Parkinson's Disease·Giorgia PonsiSalvatore Maria Aglioti
Jun 8, 2021·Neuroscience and Biobehavioral Reviews·Janet K X WrightJulie D Henry