Altered oxidative state in schoolchildren with asthma and allergic rhinitis

Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology
E BakkeheimKarin C Lødrup Carlsen

Abstract

Oxidative stress may be defined as a disruption of the balance between the level of oxidants and reductants (antioxidants), and oxidative state in children may influence the risk of asthma and allergic disease. We investigated serum antioxidant levels: selenium, vitamin E, bilirubin, albumin, uric acid and transferrin as well as the oxidant ferritin and their association with asthma and allergic rhinitis. Children of 7-12 yr with asthma (n = 50) and no asthma (controls) (n = 52) underwent skin prick test, lung function, fractional exhaled nitric oxide (FeNO) measurements and blood sampling. Allergic rhinitis was found in 23 children, 19 with asthma and four controls. Healthy children were controls without rhinitis. Asthma was associated with reduced albumin (g/l), adjusted odds ratio (aOR) (95% CI) 0.81 (0.66, 0.99) (p = 0.048) compared with healthy children in a regression analysis adjusted for age and gender. Asthma with high FeNO ≥20 ppb was associated with reduced albumin, aOR 0.60 (0.40, 0.89) (p = 0.012) compared to controls with FeNO <20. Asthma with allergic rhinitis had reduced albumin, aOR = 0.70 (0.50, 0.99) (p = 0.04), and higher ferritin levels (mg/l) [aOR = 1.04 (1.00, 1.09) p = 0.03] compared to healthy children....Continue Reading

References

Aug 28, 1999·Lancet·F J KellyT Sandström
Jun 23, 2000·Annals of the New York Academy of Sciences·J M Gutteridge, B Halliwell
Aug 15, 2000·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·H VuralO Akyol
Dec 20, 2000·Canadian Respiratory Journal : Journal of the Canadian Thoracic Society·H Vural, K Uzun
Sep 5, 2002·The Journal of Allergy and Clinical Immunology·Russell P Bowler, James D Crapo
Apr 22, 2003·The Tohoku Journal of Experimental Medicine·Takashi OhruiHidetada Sasaki
Jul 11, 2003·Chest·Eugenio BaraldiPaolo Montuschi
Feb 6, 2004·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Esther Granot, Ron Kohen
Feb 5, 2004·Thorax·G Caramori, A Papi
Jul 17, 2004·American Journal of Respiratory and Critical Care Medicine·Tricia M McKeever, John Britton
Apr 2, 2005·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Ahmed NadeemSunil K Chhabra
Apr 9, 2005·American Journal of Respiratory and Critical Care Medicine·UNKNOWN American Thoracic Society, UNKNOWN European Respiratory Society
May 26, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Gregory J QuinlanTimothy W Evans
Jun 9, 2005·The Journal of Allergy and Clinical Immunology·Graham Devereux, Anthony Seaton
Aug 2, 2005·The European Respiratory Journal·N L A MissoP J Thompson
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
May 19, 2006·The European Respiratory Journal·M TakemuraM Mishima
Apr 26, 2007·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·P-J BousquetP Burney
Jan 2, 2008·The European Respiratory Journal·E D BatemanH J Zar
Jul 3, 2008·International Journal of Hematology·Yutaka KohgoJunji Kato
Apr 28, 2009·The Journal of Pediatrics·Yakov SivanRuth Soferman
Dec 9, 2009·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·K AllanG Devereux
Jan 27, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Brooke HeidenfelderJane E Gallagher
Nov 19, 2010·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·C Sachs-OlsenK-H Carlsen

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Citations

May 25, 2011·Biological Trace Element Research·Maria Fernanda Hornos CarneiroFernando Barbosa
Apr 11, 2012·American Journal of Rhinology & Allergy·A Fusun Kalpaklioglu, Ilkay K Kalkan
Aug 15, 2014·Biological Trace Element Research·Maurício Bianchini MorescoClaudia Ramos Rhoden
Jun 26, 2013·AAPS PharmSciTech·Susanne R YoungrenMahavir B Chougule
Aug 2, 2011·Redox Report : Communications in Free Radical Research·Valentina ChiavaroliAngelika Mohn
Mar 2, 2013·Allergy, Asthma & Immunology Research·Ju-Hee SeoSoo-Jong Hong
Feb 16, 2017·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·N HämäläinenS M Virtanen
Dec 7, 2019·The European Respiratory Journal·Emmanouela SdonaAnna Bergström
Jan 7, 2021·Photodermatology, Photoimmunology & Photomedicine·Naiyu LinJiande Han
Feb 15, 2021·Allergy·Angela MessinaAndrea Leonardi
Aug 31, 2021·International Journal of Circumpolar Health·Birgitte Hamann LaustsenJakob Hjort Bønløkke

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