Altered risky decision making in patients with early non-affective psychosis.

European Archives of Psychiatry and Clinical Neuroscience
Luk MskChen Eyh

Abstract

Abnormal risky decision making may represent an important factor contributing to functional impairment in psychotic disorders. Previous research revealed impaired decision making under risk in patients with chronic schizophrenia. However, risky decision making is under-studied in the early course of illness. We examined risky decision making in 33 patients with early non-affective psychosis and 32 demographically matched controls, using two well-validated experimental paradigms, balloon analogue risk task (BART) and Risky-Gains task (RGT), which modeled and assessed actual risk-taking behaviors in deliberative and time-pressured decision-making situations, respectively. Our results showed that patients exhibited suboptimal decision making on the BART and were more risk averse than controls by having fewer average balloon pumps in non-burst trials, lower explosion rate and lower total points gained. On the RGT, patients also behaved more conservatively than controls, with lower overall rate in choosing the risky option. Intriguingly, patients performed comparably to controls in adjusting risk-taking pattern following punished trials, suggesting relatively preserved sensitivity to punishment in early psychosis. Risk-taking measur...Continue Reading

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Citations

Sep 29, 2019·European Archives of Psychiatry and Clinical Neuroscience·Junya FujinoHidehiko Takahashi
Dec 7, 2021·Frontiers in Psychiatry·Sandra Chi Yiu WongWing Chung Chang

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