Altered T and B lymphocyte signaling pathways in lupus

Autoimmunity Reviews
Stanford L Peng

Abstract

Systemic lupus erythematosus (SLE) has long been recognized to be characterized by dysregulated signaling pathways in T and B lymphocytes, beginning with observations of cellular hyperactivity and hyperresponsiveness, and evolving to recent studies focused upon the genetic and molecular bases of such phenomena. This review focuses on recently elucidated signaling abnormalities currently thought to be intrinsic to T and/or B cells in human SLE.

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Citations

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Sep 25, 2012·Autoimmunity Reviews·Mariele GattoAndrea Doria
Oct 14, 2014·Autoimmunity Reviews·Jieyue LiaoQianjin Lu
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Aug 19, 2010·Autoimmunity Reviews·Carlo Selmi
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Jan 14, 2021·Biology of Sex Differences·Maria Luisa DupuisElena Ortona
Aug 12, 2019·Autoimmunity Reviews·Ommar OmarjeeAlexandre Belot

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