Altering risky decision-making: Influence of impulsivity on the neuromodulation of prefrontal cortex

Social Neuroscience
Gordon L F Cheng, Tatia M C Lee

Abstract

The prefrontal cortex (PFC) subserves complex cognitive abilities, including risky decision-making; the modulation of this brain area is shown to alter the way people take risks. Yet, neuromodulation of the PFC in relation to risk-taking behavior remains relatively less well-studied. Moreover, the psychological variables that influence such neuromodulation remain poorly understood. To address these issues, 16 participants took part in 3 experimental sessions on separate days. They received: (i) left anodal-right cathodal transcranial direct current stimulation (tDCS); (ii) left cathodal-right anodal stimulation; or (iii) sham stimulation while they completed two risk-taking tasks. They also measured on several cognitive-affective abilities and personality traits. It was revealed that left cathodal-right anodal stimulation led to significantly reduced risk-taking under a context of haste. The reduction of risk-taking (relative to sham) correlated with state and trait impulsivity, such that the effect was larger in more impulsive individuals. For these individuals, the tDCS effect size was considered to be large (generalized partial η(2) > .17). The effect of prefrontal-neuromodulation in reducing risk-taking was influenced by ba...Continue Reading

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Citations

Dec 7, 2018·Journal of the International Neuropsychological Society : JINS·Jaan Tulviste, Talis Bachmann
Oct 28, 2018·European Archives of Psychiatry and Clinical Neuroscience·Ahmet Zihni SoyataSacit Karamürsel
May 18, 2020·Psychiatry and Clinical Neurosciences·Ali KhaleghiMohammad Reza Mohammadi
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Dec 19, 2019·Brain Stimulation·Benjamin C GibsonVincent P Clark
Nov 13, 2019·Progress in Neuro-psychopharmacology & Biological Psychiatry·Juliana Teti MayerDjamila Bennabi

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