Alternaria is an Infrequent Cause of Keratitis: A Case Report and Review of the Literature

Eye & Contact Lens
Rosa MonnoMaurizio Sanguinetti

Abstract

To report a case of fungal keratitis caused by Alternaria in a 49-year-old female who developed an acute onset of eye infection after ocular trauma caused by an olive leaf. The clinical presentation, microbiological diagnosis, and therapeutic approaches are reported. The patient was referred to our university hospital clinic with corneal abscess in her left eye. Before the start of an empirical antibacterial therapy (both topical and systemic), a swab of the cornea was obtained which at microscopic examination revealed a few fragments of hyphal elements, probably for the paucity of material collected. After one week, the corneal abscess had increased in size, and the corneal stroma was filled with filamentous structures similar to fungal hyphae. Oral and topical voriconazole was administered because of the clinical picture and the response of microbiological laboratory whose examination of the material removed from the anterior chamber showed numerous hyphal fragments identified by culture as Alternaria spp. The corneal abscess healed in two weeks, but the patient now has a corneal scar and is awaiting a corneal transplant. Ophthalmologists and microbiologists must take fungi into greater consideration as a possible cause of ke...Continue Reading

References

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Citations

Dec 3, 2016·Eye & Contact Lens·Rosa MonnoGiuseppe Miragliotta
Dec 25, 2019·Current Eye Research·Pranita SahayJeewan S Titiyal
Jan 20, 2021·Journal of Applied Microbiology·M RaiM Alves

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